Research and analysis

Invasive meningococcal disease (laboratory reports in England): January to March 2014

Updated 26 September 2014

In England between January and March 2014, a total of 211 cases of invasive meningococcal disease (IMD) were reported to Public Health England [1]. This was a 14% decrease from the 245 cases reported in the first quarter of 2013 and a 15% increase from the 183 cases reported in the last quarter of 2013. Eleven cases of IMD were reported in this period in Wales.

Of the 211 cases of IMD reported in England; 63% (132) were capsular group B, 16% (33) group Y and group W, 5% (10) group C and three cases were ungrouped. Of the eleven IMD cases reported to PHE from Wales: seven were capsular group B, two group Y, one group W and one ungroupable. During the first quarter of 2014 there were no reported cases for capsular groups A, X and Z/E (table1) in England or Wales.

Fifty-one per cent (105/207) of IMD cases reported in England were female. In England, children aged less than one year accounted for 21% (45/21 1) of IMD reports. The majority of infant cases (58%; [26/45]) were aged between six and 11 months, and of these 24 were group B and two were group W. In 19 infants with IMD aged between zero and five months, 14 had capsular group B, four were group W and one was ungrouped. Almost a fifth (18%; [38/211]) of cases were in children aged between one and four years of which 89% (34/38) were capsular group B disease, one group C and W and two ungrouped (table 2). More than half of the capsular group B cases (55%; [72/132]) were in children under 5 years of age. Of the 33 capsular group Y disease, the majority (79%; [26/33]) were in adults aged 45 and over and similarly the majority of group W cases were in individuals aged 45 and older (61%; [20/33]).

0.1 Table 1. Invasive meningococcal disease in England by capsular group and laboratory testing method, weeks 1-13 (Q1): 2013 and 2014*

See separate spreadsheet for Table 1.

0.2 Table 2. Invasive meningococcal disease in England by capsular group and age at diagnosis, weeks 1-13 (Q1), 2014

Capsular group <1 1-4 5-9 10-14 15-19 20-24 25-44 45-64 65+ Total
B 38 34 9 2 15 6 12 8 8 132
C 1 2 2 1 4 10
W 6 1 2 2 2 6 14 33
Y 2 5 7 19 33
Ungrouped 1 2 3
Total 45 38 11 4 17 10 20 25 41 211

0.3 Reference

  1. Data source: Public Heath England Meningococcal Reference Unit

Published in Health Protection Report volume 8 issue 25.