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Guidance

Appendix A: the number of hepatitis-B containing vaccine doses for children – text version

Updated 18 September 2026

Applies to England

© Crown copyright 2026

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This publication is available at https://www.gov.uk/government/publications/hexavalent-combination-vaccine-programme-guidance/appendix-a-the-number-of-hepatitis-b-containing-vaccine-doses-for-children-text-version

See also comprehensive guidance on hepatitis B antenatal screening and the selective neonatal pathway and the Green Book chapter 18: hepatitis B.

Child born to a woman living with hepatitis B

Six doses of hep B containing vaccine (+/- HBIG) and testing between one year and 18 months of age as per selective neonatal hepatitis B pathway

  • monovalent hepatitis B vaccine (+/- HBIG) given at birth 
  • second dose of monovalent hepatitis B vaccine at 4 weeks of age
  • DTaP/IPV/Hib/HepB hexavalent vaccines at 8, 12, 16 weeks and 18 months of age as per new routine childhood immunisation schedule
  • test for HBsAg at anytime between one year and 18 months of age

Child living in a household where someone is living with hepatitis B

This refers to those sharing a household with an individual other than their mother who is living with hepatitis B.

Five doses of hep B containing vaccine as per Green Book guidance

  • monovalent hepatitis B vaccine should be offered before discharge from hospital (as per Green Book) 

  • give DTaP/IPV/Hib/HepB hexavalent vaccines at 8, 12, 16 weeks and 18 months of age as per new routine childhood immunisation schedule

Routine schedule of hep B containing vaccine for all children

Four doses of hep B containing vaccine

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