Understanding your ISA report
Published 20 February 2026
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As part of the Integrated Scientific Advice (ISA) service the Medicines and Healthcare products Regulatory Agency (MHRA) and National Institute for Health and Care Excellence (NICE) have a single report structure.
Timings, receipt and clarifications
Receiving the report
Following the advice meeting MHRA and NICE have 6 weeks to jointly write and review the report.
The report and instructions on how to access it will be sent to the advice enquirer via NICE Docs.
How to request clarification questions
During the process of organising your advice request you will have a named project manager to contact. To ask a clarification question after receiving your report email your contact with your questions. These questions cannot be new. They should only clarify currently requested advice discussed during the Integrated Scientific Advice meeting.
Further information and how to get in touch
Further information
Request Integrated Scientific Advice
See detailed guidance on Integrated Scientific Advice
See supplementary information on the ISA service