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Guidance

Clinical trials for medicines: roles and responsibilities

Which professions can act as an investigator, training and experience expectations, provision of medical support and delegation of activities.

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Details

The amended Clinical Trials Regulations took full effect on 28 April 2026. As such, this guidance should now be considered effective and is no longer in draft.

The following guidance accompanies the Medicines for Human Use (Clinical Trials) Regulations 2004, as amended by the Medicines for Human Use (Clinical Trials) (Amendment) Regulations 2025.

Part 2 of Schedule 1 to the amended Clinical Trials Regulations requires that the investigator and sponsor have regard to all relevant guidance with respect to commencing and conducting a clinical trial.

Updates to this page

Published 16 April 2026
Last updated 28 April 2026 show all updates
  1. The amended Clinical Trials Regulations took full effect on 28 April 2026. As such, this guidance should now be considered effective and is no longer in draft.

  2. First published.

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