Notice

CDE themed competition: innate response targets for therapy

Further information on this Centre for Defence Enterprise (CDE) competition for research funding.

From:
Defence Science and Technology Laboratory and Centre for Defence Enterprise
Published
30 June 2014

Documents

Innate response targets for therapy competition document

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Details

This competition closes on Thursday 5 June 2014 at 5pm. Proposals must be submitted through the CDE portal.

Summary of this competition

Total funding available for this competitions is £480k.

This competition closes on Thursday 5 June 2014 at 5pm.

The Ministry of Defence seeks to identify host-pathogen interactions that can be manipulated to devise novel and generic therapies to meet the UK’s current and future defence and security needs. Such therapies should have broad activity against diverse microbial (bacterial and viral) challenges. Ideally, the solutions to such challenges will not be dependent on prior knowledge of the biothreat.

To this end, we seek novel approaches to directing host responses for protection, therapy and survival.

The purpose of this CDE themed competition for proof-of-concept research proposals is to reach out to all sectors for highly innovative techniques, tools and approaches to facilitate the identification of therapies or the early stages of therapeutic development by:

  • the identification of novel host cell or pathway targets and demonstrating that they can be exploited for beneficial outcome eg to prevent cytotoxicity, prevent microbial invasion and restore normal cell functioning
  • the identification of new candidate therapies, or re-purposed or augmented existing therapies, which may, for example, enhance cell-mediated immunity or modulate natural regulators
  • the identification of new platform technologies, which support these challenges, such as non-invasive methods of in-vivo/ex-vivo analysis, transcriptomics, in-silico modelling of host responses, or novel assays to monitor the immune response

This competition launched at our Innovation Network event in March 2014.

View the presentation slides that were briefed at the event

This competition closes on Thursday 5 June 2014 at 5pm. Proposals must be submitted through the CDE portal.

Centre for Defence Enterprise

Building R103
Fermi Avenue
Harwell Oxford
Oxfordshire
OX11 0QX

Email cde@dstl.gov.uk

Telephone +44 (0)30 67704236

Alternative number +44 (0)30 67704237

Please email for the quickest response.

Published 30 June 2014

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