Guidance

Acute flaccid paralysis: clinical management guidance

Information on the clinical management of acute flaccid paralysis (AFP) and acute flaccid myelitis (AFM), for use by healthcare professionals.

• From: UK Health Security Agency
• Published: 19 December 2018
• Last updated: 3 April 2025
  Show all updates

  1. 3 April 2025

     Updated information on notification regulations.

  2. 15 November 2022

     Updated 'Clinical management of acute flaccid paralysis or acute flaccid myelitis'.

  3. 25 October 2021

     Updated clinical management guidance.

  4. 12 June 2019

     Updated long-term outcomes section.

  5. 19 December 2018

     First published.

Applies to England

Documents

Clinical management of acute flaccid paralysis or acute flaccid myelitis

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Details

This guidance summarises the existing information on clinical management of acute flaccid paralysis (AFP) and acute flaccid myelitis (AFM).

The document includes:

• details of immunological and antiviral therapies
• an overview of long-term outcomes
• infection control procedures

It is intended for use by healthcare professionals.