This challenge aims to develop an effective data strategy and data management structure to map the developmental and reproductive toxicity (DART) genes of different species. You should compare the effects of toxic compounds across species.
It is in 2 phases. There is up to £100,000 each for 3 projects in phase 1. Phase 2 has funding of up to £1 million. Shell and Syngenta are the sponsors.
Challenge 27 - Dosing for controlled exposure (DoCE)
This challenge aims to improve dosing methods and strategies for in vitro dose-responses and to encourage their uptake, application and use in risk-based decision making. This could offer the potential to eventually replace the need for in vivo animal studies.
It is in 2 phases. There is up to £100,000 each for 3 projects in phase 1. Phase 2 has funding of up to £1 million. Unilever and Shell are the sponsors.
The single-phase challenge is:
Challenge 28 - RespiraTox
In this challenge the aim is to develop a model that reliably predicts human respiratory irritation to chemicals. It should use in silico-based tools.
This is a single-phase competition. Up to £100,000 is available. The competition is sponsored by Shell.
NC3Rs is an independent scientific organisation that supports the UK science base to find alternative applications to the use of animals in research and improve welfare.
The challenges are run using the Small Business Research Initiative (SBRI), which is supported by Innovate UK.
Corrected the amount of funding available in the 2-phase competitions. These will fund up to 3 projects for up to £100,000 each in phase 1. This brings the total available across the 3 challenges to £2.7 million.