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Lassa fever cases identified in England, following travel to West Africa

Latest updates on cases of Lassa fever identified in England.

Latest update

The UK Health Security Agency (UKHSA) can confirm that the monitoring periods, for contacts of the Lassa fever cases who required active monitoring, have now been completed. No further cases have been identified. We would like to thank our partners in the NHS for their prompt action and all of the contacts for their cooperation.
 
The Royal Free London NHS Foundation Trust has confirmed that the patient has been discharged.

Previous updates

Wednesday 16 February 2022

UKHSA continues to follow up and closely monitor individuals identified as contacts of 3 recently confirmed cases of Lassa fever. No further cases have been identified to date.

NHS Trusts have performed risk assessments on individuals and patients who have worked or stayed in the same ward areas as the Lassa patients. Individuals have been given advice on monitoring and testing. The majority of individuals will complete monitoring by early March.

The risk to the general public remains very low.

Friday 11 February 2022

UKHSA can confirm that the probable case of Lassa fever under investigation is now confirmed, bringing the total number of cases to 3. Sadly, this individual has died.

We are contacting the individuals who have had close contact with the cases prior to confirmation of their infection, to provide appropriate assessment, support and advice. The risk to the general public remains very low.

A Bedfordshire Hospitals NHS Foundation Trust spokesperson said:

We confirm the sad death of a patient at our trust, who had confirmed Lassa fever. We send our deepest condolences to their family at this difficult time.

We will continue to support the patient’s family and our staff and are working closely with colleagues from UKHSA to undertake a robust contact tracing exercise.

Wednesday 9 February 2022

Two people diagnosed with Lassa fever in England

A further probable case of Lassa fever is under investigation. The cases are within the same family in the East of England and are linked to recent travel to West Africa.

Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus. People usually become infected with Lassa virus through exposure to food or household items contaminated with urine or faeces of infected rats – present in a number of West African countries where the disease is endemic. The virus can also be spread through infected bodily fluids.

Most people with Lassa fever will make a full recovery, however severe illness can occur in some individuals. One of the cases has recovered, while the other will receive specialist care at the Royal Free London NHS Foundation Trust.

The probable case is receiving care at Bedfordshire Hospitals NHS Foundation Trust. The High Consequence Infectious Disease Network is engaged with their ongoing care.

Dr Susan Hopkins, Chief Medical Advisor at UKHSA, said:

We can confirm that 2 cases of Lassa fever have been identified in England, and a further probable case is under investigation. The cases are within the same family and are linked to recent travel to West Africa.

Cases of Lassa fever are rare in the UK and it does not spread easily between people. The overall risk to the public is very low. We are contacting the individuals who have had close contact with the cases prior to confirmation of their infection, to provide appropriate assessment, support and advice.

UKHSA and the NHS have well established and robust infection control procedures for dealing with cases of imported infectious disease and these will be reinforced.

Prior to these cases, there have been 8 cases of Lassa fever imported to the UK since 1980. The last 2 cases occurred in 2009. There was no evidence of onward transmission from any of these cases.

Dr Sir Michael Jacobs, consultant in infectious diseases at the Royal Free London, said:

The Royal Free Hospital is a specialist centre for treating patients with viral haemorrhagic fevers, including Lassa fever.

Our secure unit is run by a highly-trained and experienced team of doctors, nurses, therapists and laboratory staff and is designed to ensure our staff can safely treat patients with these kind of infections.

People living in endemic areas of West Africa with high populations of rodents are most at risk of Lassa fever. Imported cases rarely occur elsewhere in the world. Such cases are almost exclusively in people who work in endemic areas in high-risk occupations, such as medical or other aid workers.

Published 9 February 2022
Last updated 4 March 2022 + show all updates
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