The Foreign and Commonwealth Office advise against all but essential travel to areas of Uzbekistan bordering Afghanistan.
Take care in areas bordering Tajikistan and Kyrgyzstan. Uzbekistan’s borders are potential flashpoints and uncontrolled border areas may be land-mined. Borders are subject to closure without notice. See Local travel
Take care if you travel to the Fergana Valley due to continuing tensions in the region.
There is an underlying threat from terrorism. See Terrorism.
Foreign nationals have been detained on arrival for possession of medicines that would not normally be problematic in other countries. See Travelling with medicines
Most visits to Uzbekistan are trouble free.
Take out comprehensive travel and medical insurance before you travel.