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Drug Safety Update

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110 updates

About Psychiatry

Antipsychotics: risk of venous thromboembolic events

Use of Antipsychotic may be associated with an increased risk of venous thromboembolic events.
- Therapeutic area: Psychiatry
- Published: 11 December 2014
Chloral hydrate (Welldorm) and Triclofos

These medicines are not first-line options for insomnia.
- Therapeutic area: Paediatrics and neonatology and 1 others
- Published: 11 December 2014
Methylphenidate: safe and effective use to treat ADHD

Updated guidance to use methylphenidateto safely and effectively for attention deficit hyperactivity disorder (ADHD) in children of 6 years or older and adolescents.
- Therapeutic area: Paediatrics and neonatology and 1 others
- Published: 11 December 2014
Atomoxetine: risk of psychotic or manic symptoms in children and adolescents

Atomoxetine is associated with treatment-emergent psychotic or manic symptoms in children and adolescents - consider stopping this if symptoms occur.
- Therapeutic area: Paediatrics and neonatology and 1 others
- Published: 11 December 2014
Antidepressants: suicidal thoughts and behaviour

Summary report on the risk of suicidal thoughts and behaviour related to antidepressants.
- Therapeutic area: Psychiatry
- Published: 11 December 2014
Ecoflac infusion solutions: risk of air embolism

To avoid the risk of air embolism, these products should not be infused under pressure.
- Therapeutic area: Anaesthesia and intensive care and 22 others
- Published: 11 December 2014
Botulinum toxin products: rare but serious risks

Products that contain botulinum toxin are associated with the risk of serious adverse reactions due to distant spread of toxin.
- Therapeutic area: Neurology and 1 others
- Published: 11 December 2014
Lorazepam: reduction of recommended maximum daily dose

Maximum dose of lorazepam for short term, symptomatic treatment is 4 mg per day for severe, disabling anxiety, and 2 mg per day for severe, disabling insomnia
- Therapeutic area: Psychiatry
- Published: 11 December 2014
Pabrinex: allergic reactions

Rare occurrence of serious allergic reactions should not preclude use of parenteral thiamine in patients who need treatment by this route of administration.
- Therapeutic area: Nutrition and dietetics and 1 others
- Published: 11 December 2014
Duloxetine: marketed as Cymbalta▼ and Yentreve▼ for different disorders

Patients should be assessed regularly due to reported cases of suicidal ideation and suicidal behaviour during treatment with duloxetine or shortly after stopping treatment.
- Therapeutic area: Endocrinology, diabetology and metabolism and 2 others
- Published: 11 December 2014

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