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Drug Safety Update

From:
Medicines and Healthcare products Regulatory Agency
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  • Statins: very infrequent reports of myasthenia gravis

    Globally, there has been a very small number of reports of new-onset or aggravation of pre-existing myasthenia gravis with atorvastatin, pravastatin, lovastatin, fluvastatin, simvastatin, rosuvastatin and pitavastatin (single-ingredient and fixed-dose combination products).…

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published:
  • Statins: interactions, and updated advice for atorvastatin

    Detailed recommendations for dose restrictions when used with some other drugs as interactions may increase the risk of adverse effects, or reduce the effectiveness of statin treatment.

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published:
  • Systemic fusidic acid and interaction with statins

    There is a risk of rhabdomyolysis if Systemic fusidic acid (Fucidin) is given with statins.

    • Therapeutic area: Cardiovascular disease and lipidology and 1 others
    • Published:
  • Statins: updated adverse reaction information in patient leaflets

    Healthcare professionals should be aware of the updated information so they can discuss it with new and existing patients.

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published:
  • Statins: benefits and risks

    Statins (HMG-CoA reductase inhibitors) are widely used medicines for patients with lipid disorders and in the primary and secondary prevention of heart attack and stroke.

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published: