Skip to main content

Drug Safety Update

From:
Medicines and Healthcare products Regulatory Agency
Skip to results
  • Modafinil (Provigil): increased risk of congenital malformations if used during pregnancy

    Modafinil potentially increases the risk of congenital malformations when used in pregnancy. Modafinil should not be used during pregnancy and women of childbearing potential must use effective contraception during treatment and for 2 months after stopping modafinil.…

    • Therapeutic area: Neurology and 1 others
    • Published:
  • Modafinil: restricted use recommended

    European Medicines Agency has recommends the use of modafinil should be restricted to treat only sleepiness associated with narcolepsy - should no longer be used for obstructive sleep apnoea or chronic shift work sleep disorder.

    • Therapeutic area: Neurology and 1 others
    • Published:
  • Modafinil (Provigil): now restricted to narcolepsy

    Further information is available to support safer use

    • Therapeutic area: Neurology
    • Published:
  • Letters and drug alerts sent to healthcare professionals in January 2020

    …Letters were sent about methotrexate, modafinil, Ecalta, Picato, Nexplanon, valproate medicines, e-cigarettes, and Lemtrada. Alerts were issued about finasteride, codeine/paracetamol, and Picato.…

    • Therapeutic area: Anaesthesia and intensive care and 10 others
    • Published: