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Drug Safety Update

From:
Medicines and Healthcare products Regulatory Agency
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  • Statins: interactions, and updated advice for atorvastatin

    Detailed recommendations for dose restrictions when used with some other drugs as interactions may increase the risk of adverse effects, or reduce the effectiveness of statin treatment.

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published:
  • Simvastatin: increased risk of myopathy at high dose (80 mg)

    There is an increased risk of myopathy associated with high-dose (80 mg) simvastatin. The 80-mg dose should be considered only in patients with severe hypercholesterolaemia and high risk of cardiovascular complications who h…

    • Therapeutic area: Cardiovascular disease and lipidology
    • Published: