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Modafinil potentially increases the risk of congenital malformations when used in pregnancy. Modafinil should not be used during pregnancy and women of childbearing potential must use effective contraception during treatment and for 2 months after stopping modafinil.
European Medicines Agency has recommends the use of modafinil should be restricted to treat only sleepiness associated with narcolepsy - should no longer be used for obstructive sleep apnoea or chronic shift work sleep disorder.
The review of the safety of isotretinoin has concluded.
Further information is available to support safer use
Being honest and transparent with online reviews and endorsements, including on social media and in other online content.
How to use feedback from marketplace reviews to evaluate your digital health product.
Information and documents on Public Health England’s review of the evidence for dependence on, and withdrawal from, prescribed medicines.
Review of the evidence of misuse and harm in relation to the benzofuran-type substances.
Guidance for sites that publish online reviews on how to ensure that users get a full, accurate picture of reviewers’ experiences.
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