Research and analysis
NOIDs causative agents: week 10 (week ending 12 March 2023)
Updated 2 January 2024
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NOIDs weekly report
Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia lamblia
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Influenza virus
- Junin virus
- Kyasanur Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- Measles virus
- Mpox (monkeypox) virus
- Mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium knowlesi
- Plasmodium malariae
- Plasmodium ovale
- Plasmodium vivax
- Polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
| Week notification received | 2023/05 | 2023/06 | 2023/07 | 2023/08 | 2023/09 | 2023/10 |
|---|---|---|---|---|---|---|
| Bacillus | ||||||
| Bacillus cereus | 14 | 20 | 34 | 11 | 19 | 18 |
| Bordetella | ||||||
| Bordetella pertussis | 1 | 2 | 1 | 3 | 4 | 2 |
| Borrelia | ||||||
| Borrelia burgdorferi | 17 | 14 | 19 | 12 | 6 | 11 |
| Borrelia sp | 1 | 2 | - | 11 | 4 | 7 |
| Borrelia tillae | - | 1 | - | - | - | - |
| Campylobacter | ||||||
| Campylobacter coli | 13 | 20 | 14 | 11 | 17 | 7 |
| Campylobacter fetus | 1 | - | - | 1 | 1 | 1 |
| Campylobacter gracilis | - | - | 1 | - | - | - |
| Campylobacter jejuni | 202 | 237 | 181 | 188 | 238 | 140 |
| Campylobacter lari | - | 1 | - | - | - | - |
| Campylobacter other named | 1 | 1 | - | 2 | 1 | - |
| Campylobacter sp | 720 | 644 | 589 | 720 | 675 | 637 |
| Campylobacter upsaliensis | 1 | 1 | - | 1 | - | - |
| Campylobacter ureolyticus (bacteroides corrodens) | - | - | - | 1 | - | - |
| Chikungunya virus | ||||||
| Chikungunya virus | 2 | - | - | 2 | - | - |
| Clostridium | ||||||
| Clostridium perfringens | 42 | 34 | 31 | 35 | 33 | 36 |
| Coronavirus | ||||||
| Coronavirus | 173 | 194 | 105 | 163 | 112 | 103 |
| Human coronavirus 229e | 1 | - | - | - | - | - |
| SARS coronavirus | - | - | - | - | 1 | - |
| SARS-CoV-2 antibody indeterminate | 165 | 90 | 221 | 175 | 138 | 163 |
| SARS-CoV-2 antibody void | 2 | 10 | 14 | 5 | - | 8 |
| SARS-CoV-2 coronavirus (COVID- 19) | 20,919 | 21,594 | 26,643 | 24,310 | 25,024 | 27,766 |
| SARS-CoV-2 coronavirus (COVID-19) indeterminate | 235 | 419 | 327 | 341 | 374 | 344 |
| SARS-CoV-2 IgG antibody negative | 226 | 168 | 124 | 211 | 95 | 222 |
| SARS-CoV-2 IgG antibody positive | 955 | 1,122 | 976 | 819 | 398 | 915 |
| SARS-CoV-2 total antibody negative | 193 | 278 | 316 | 216 | 148 | 116 |
| SARS-CoV-2 total antibody positive | 692 | 868 | 856 | 572 | 522 | 474 |
| Corynebacterium | ||||||
| Corynebacterium diphtheriae | 3 | - | 1 | - | - | 1 |
| Corynebacterium ulcerans | 1 | 2 | - | - | - | - |
| Coxiella | ||||||
| Coxiella burnetii | 1 | - | - | - | - | - |
| Cryptosporidium | ||||||
| Cryptosporidium cuniculus | - | - | - | 1 | - | - |
| Cryptosporidium felis | - | - | - | - | 1 | - |
| Cryptosporidium hominis | 9 | 11 | 8 | 9 | 10 | 4 |
| Cryptosporidium novel genotype | - | - | 1 | - | - | - |
| Cryptosporidium parvum | 31 | 7 | 17 | 14 | 15 | 4 |
| Cryptosporidium sp | 22 | 20 | 12 | 15 | 22 | 32 |
| Cryptosporidium ubiquitum | - | 1 | 1 | - | - | - |
| Entamoeba | ||||||
| Entamoeba histolytica | 4 | - | 2 | - | 1 | - |
| Escherichia | ||||||
| Escherichia coli O 157 | 4 | 7 | 4 | 5 | 6 | 3 |
| Flaviviruses | ||||||
| Dengue virus | 3 | - | - | 4 | - | - |
| Haemophilus | ||||||
| Haemophilus influenzae | 63 | 81 | 71 | 85 | 69 | 70 |
| Hepatitis viruses | ||||||
| Hepatitis A | 16 | 8 | 16 | 12 | 17 | 8 |
| Hepatitis B | 238 | 329 | 206 | 327 | 252 | 211 |
| Hepatitis C | 269 | 315 | 290 | 365 | 350 | 280 |
| Hepatitis D | 1 | 10 | 1 | 9 | 3 | 3 |
| Hepatitis E | 32 | 19 | 27 | 33 | 21 | 18 |
| Influenza virus | ||||||
| Influenza A | 486 | 345 | 258 | 1,212 | 163 | 145 |
| Influenza B | 532 | 569 | 639 | 616 | 528 | 546 |
| Influenza indeterminate | 16 | 12 | 28 | 14 | 11 | 19 |
| Influenza ungrouped | 21 | 16 | 13 | 6 | - | 6 |
| Legionella | ||||||
| Legionella other named | - | - | - | - | 1 | - |
| Legionella pneumophila | 1 | 2 | 4 | 3 | 1 | 1 |
| Legionella sp | 1 | 2 | 1 | 2 | 3 | 5 |
| Listeria | ||||||
| Listeria monocytogenes | - | 5 | 3 | 1 | 4 | 2 |
| Mycobacterium | ||||||
| Mycobacterium tuberculosis | 69 | 79 | 84 | 121 | 79 | 75 |
| Neisseria | ||||||
| Neisseria meningitidis | 15 | 15 | 10 | 15 | 12 | 14 |
| Orthopoxvirus | ||||||
| Mpox virus | 1 | 1 | 1 | 1 | - | - |
| Paramyxoviruses | ||||||
| Measles virus | 8 | 4 | 3 | 3 | 2 | 3 |
| Mumps virus | 6 | 3 | 3 | 1 | 5 | 16 |
| Plasmodium | ||||||
| Plasmodium falciparum | 28 | 3 | 4 | 8 | 1 | 11 |
| Plasmodium malariae | - | - | - | 1 | - | - |
| Plasmodium ovale | 3 | - | - | 1 | - | 1 |
| Plasmodium vivax | - | - | - | 1 | - | - |
| Polyomavirus | ||||||
| Polyomavirus BK | 44 | 42 | 40 | 47 | 43 | 52 |
| Polyomavirus JC | 8 | 9 | 1 | 7 | 10 | 7 |
| Polyomavirus untyped | - | - | 1 | 2 | 1 | - |
| Rickettsia | ||||||
| Rickettsia sp | - | - | - | - | - | 1 |
| Rubella virus | ||||||
| Rubella virus | 2 | 5 | 5 | 5 | 4 | 5 |
| Salmonella | ||||||
| Other salmonellas | 48 | 38 | 43 | 55 | 34 | 24 |
| Salmonella enteritidis | 16 | 29 | 19 | 17 | 12 | 5 |
| Salmonella infantis | - | 7 | - | - | - | - |
| Salmonella mbandaka | 6 | - | - | - | - | - |
| Salmonella newport | - | 5 | - | - | - | - |
| Salmonella sp | 18 | 12 | 17 | 18 | 127 | 95 |
| Salmonella typhi and paratyphi | 17 | 9 | 10 | 12 | 14 | 7 |
| Salmonella typhimurium | 17 | 14 | 10 | 16 | 9 | 19 |
| Salmonella virchow | - | 5 | - | - | - | - |
| Shigella | ||||||
| Shigella boydii | 1 | 2 | 2 | 1 | 2 | - |
| Shigella dysenteriae | - | 1 | 1 | - | - | 2 |
| Shigella flexneri | 13 | 16 | 12 | 17 | 22 | 19 |
| Shigella sonnei | 17 | 17 | 14 | 16 | 11 | 15 |
| Shigella sp | 37 | 34 | 42 | 64 | 134 | 63 |
| Streptococcus | ||||||
| Streptococcus group A | 95 | 115 | 125 | 106 | 111 | 139 |
| Streptococcus pneumoniae | 117 | 140 | 137 | 132 | 106 | 144 |
| Vibrio | ||||||
| Vibrio cholerae | - | - | - | - | 1 | - |
Carbapenemase-producing Enterobacterales (CPE)*
Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2023/05 | 2023/06 | 2023/07 | 2023/08 | 2023/09 | 2023/10 | |
|---|---|---|---|---|---|---|---|
| Citrobacter | |||||||
| Citrobacter spp | IMP | - | - | - | - | 2 | - |
| KPC | - | 1 | 1 | 1 | 1 | - | |
| NDM | 1 | - | 2 | - | - | - | |
| OXA48 | 1 | 2 | 1 | - | - | - | |
| VIM | - | 1 | - | - | - | - | |
| Enterobacter | |||||||
| Enterobacter cloacae complex | IMP | - | - | 1 | - | 2 | - |
| KPC | 4 | 1 | 4 | 2 | 4 | 1 | |
| NDM | 3 | 5 | 1 | 2 | 2 | 2 | |
| OXA48 | - | - | - | - | 1 | - | |
| VIM | - | - | 1 | - | - | - | |
| Other | - | 1 | 1 | - | - | 1 | |
| Other enterobacter spp | IMP | - | - | - | - | 1 | - |
| KPC | - | - | - | - | 1 | - | |
| NDM | 1 | - | 1 | 1 | - | - | |
| Escherichia | |||||||
| Escherichia coli | IMP | - | - | - | - | 1 | - |
| KPC | 1 | 9 | 6 | 6 | 6 | 5 | |
| NDM | 14 | 6 | 5 | 12 | 10 | 5 | |
| OXA48 | 5 | 5 | 9 | 11 | 11 | 3 | |
| VIM | - | - | - | 1 | - | - | |
| Other | 2 | - | - | - | 1 | 1 | |
| Klebsiella | |||||||
| Klebsiella aerogenes | KPC | - | - | - | - | 1 | - |
| OXA48 | - | - | - | 1 | - | - | |
| Klebsiella oxytoca | KPC | 1 | 1 | 1 | 2 | 2 | - |
| NDM | - | - | 1 | 1 | - | - | |
| OXA48 | 1 | 1 | - | - | - | - | |
| Klebsiella pneumoniae | IMP | - | - | - | - | 1 | - |
| KPC | 8 | 4 | 6 | 13 | 4 | 3 | |
| NDM | 7 | 4 | 3 | 5 | 9 | 3 | |
| OXA48 | 3 | 7 | 10 | 4 | 3 | 2 | |
| VIM | 2 | 1 | 1 | - | - | - | |
| Other | 1 | - | 1 | - | 1 | - | |
| Klebsiella variicola | NDM | - | 1 | - | - | - | - |
| OXA48 | - | 1 | - | - | - | - | |
| Other klebsiella spp | OXA48 | - | 1 | - | 1 | - | - |
| Leclercia | |||||||
| Leclercia adecarboxylata | KPC | - | - | 1 | - | - | - |
| NDM | - | - | 1 | - | - | - | |
| Pluralibacter | |||||||
| Pluralibacter spp | KPC | - | - | - | 1 | - | - |
| Serratia | |||||||
| Serratia marcescens/ureilytica | OXA48 | - | 1 | - | - | - | - |
Other carbapenemase-producing Gram-negative organisms*
Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2023/05 | 2023/06 | 2023/07 | 2023/08 | 2023/09 | 2023/10 | |
|---|---|---|---|---|---|---|---|
| Acinetobacter | |||||||
| Acinetobacter baumannii | IMP | - | - | - | 1 | - | - |
| NDM | - | - | 2 | 1 | - | 1 | |
| Other acinetobacter spp | NDM | - | - | 1 | - | - | - |
| Pseudomonas | |||||||
| Pseudomonas aeruginosa | IMP | - | - | - | 2 | - | - |
| NDM | - | - | - | - | 1 | - | |
| VIM | - | 3 | - | - | 1 | - | |
| Other | 3 | 1 | 3 | 2 | 1 | 2 | |
| Other pseudomonas spp | VIM | - | 1 | - | - | - | - |
| Other | 1 | - | - | - | - | - | |
| Other | |||||||
| KPC | - | - | - | - | 1 | - | |
| NDM | 1 | - | - | - | - | - |
*for all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.