Research and analysis
NOIDs causative agents: week 41 (week ending 16 October 2022)
Updated 16 January 2023
© Crown copyright 2023
This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gov.uk.
Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned.
This publication is available at https://www.gov.uk/government/publications/notifiable-diseases-causative-agents-reports-for-2022/noids-causative-agents-week-41-week-ending-16-october-2022
NOIDs weekly report
Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia lamblia
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Influenza virus
- Junin virus
- Kyasanur Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- Measles virus
- Monkeypox virus
- Mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium knowlesi
- Plasmodium malariae
- Plasmodium ovale
- Plasmodium vivax
- Polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
| Week notification received | 2022/36 | 2022/37 | 2022/38 | 2022/39 | 2022/40 | 2022/41 |
|---|---|---|---|---|---|---|
| Arboviruses | ||||||
| West nile virus | 1 | - | - | 1 | 1 | 1 |
| Bacillus | ||||||
| Bacillus cereus | 40 | 19 | 19 | 16 | 8 | 12 |
| Bordetella | ||||||
| Bordetella pertussis | - | - | - | 1 | - | 2 |
| Borrelia | ||||||
| Borrelia burgdorferi | 38 | 16 | 23 | 22 | 24 | 19 |
| Borrelia sp | 4 | 1 | 3 | 1 | - | 2 |
| Borrelia tillae | 5 | 1 | 1 | 2 | 1 | 2 |
| Brucella | ||||||
| Brucella melitensis | - | - | - | - | - | 1 |
| Brucella sp | 1 | - | - | 1 | - | - |
| Campylobacter | ||||||
| Campylobacter coli | 48 | 42 | 21 | 25 | 39 | 38 |
| Campylobacter fetus | - | - | - | - | 1 | - |
| Campylobacter gracilis | - | - | - | 1 | - | - |
| Campylobacter helveticus | 1 | - | - | - | - | - |
| Campylobacter jejuni | 284 | 234 | 229 | 266 | 258 | 188 |
| Campylobacter other named | 1 | - | 1 | - | - | 2 |
| Campylobacter rectus | - | 1 | 1 | - | - | - |
| Campylobacter sp | 984 | 876 | 751 | 788 | 1,552 | 845 |
| Campylobacter upsaliensis | 2 | 1 | - | - | 1 | 1 |
| Campylobacter ureolyticus (bacteroides corrodens) | 1 | - | - | 1 | 1 | - |
| Chikungunya virus | ||||||
| Chikungunya virus | 1 | 1 | 2 | 1 | - | 2 |
| Clostridium | ||||||
| Clostridium perfringens | 27 | 22 | 25 | 33 | 30 | 22 |
| Coronavirus | ||||||
| Coronavirus | 4 | 17 | 9 | 19 | 9 | 13 |
| SARS coronavirus | - | - | - | - | - | 1 |
| SARS-CoV-2 antibody indeterminate | 98 | 144 | 47 | 111 | 73 | 104 |
| SARS-CoV-2 antibody void | 24 | 13 | 9 | 6 | 11 | 32 |
| SARS-CoV-2 coronavirus (COVID-19) | 24,993 | 28,809 | 42,253 | 51,747 | 61,578 | 55,315 |
| SARS-CoV-2 coronavirus (COVID-19) indeterminate | 380 | 504 | 465 | 508 | 589 | 728 |
| SARS-CoV-2 IgG antibody negative | 332 | 461 | 270 | 356 | 366 | 339 |
| SARS-CoV-2 IgG antibody positive | 1,516 | 1,703 | 1,647 | 1,185 | 1,223 | 1,786 |
| SARS-CoV-2 IgM antibody negative | 2 | 2 | - | - | - | - |
| SARS-CoV-2 total antibody negative | 409 | 516 | 442 | 503 | 475 | 557 |
| SARS-CoV-2 total antibody positive | 1,608 | 1,538 | 1,753 | 1,516 | 1,486 | 1,672 |
| Corynebacterium | ||||||
| Corynebacterium diphtheriae | 4 | 4 | 10 | 1 | 3 | - |
| Corynebacterium ulcerans | 1 | 3 | 2 | 1 | - | - |
| Cryptosporidium | ||||||
| Cryptosporidium felis | 1 | - | - | - | - | - |
| Cryptosporidium hominis | 86 | 100 | 55 | 69 | 57 | 19 |
| Cryptosporidium meleagridis | - | - | 1 | 1 | - | - |
| Cryptosporidium parvum | 56 | 74 | 36 | 49 | 44 | 14 |
| Cryptosporidium sp | 72 | 69 | 53 | 51 | 79 | 72 |
| Entamoeba | ||||||
| Entamoeba histolytica | 1 | 2 | 2 | 3 | 2 | 4 |
| Escherichia | ||||||
| Escherichia coli O 157 | 76 | 28 | 33 | 23 | 15 | 13 |
| Flaviviruses | ||||||
| Dengue virus | 3 | 7 | 4 | 4 | 2 | 4 |
| Giardia | ||||||
| Giardia lamblia | - | 1 | 4 | 1 | 3 | 2 |
| Haemophilus | ||||||
| Haemophilus influenzae | 41 | 37 | 30 | 33 | 45 | 50 |
| Hepatitis viruses | ||||||
| Hepatitis A | 18 | 17 | 24 | 13 | 18 | 21 |
| Hepatitis B | 193 | 176 | 178 | 195 | 168 | 134 |
| Hepatitis C | 521 | 379 | 256 | 305 | 273 | 256 |
| Hepatitis D | 2 | 7 | 3 | 6 | 4 | 13 |
| Hepatitis E | 30 | 36 | 25 | 28 | 34 | 25 |
| Influenza virus | ||||||
| Influenza A | 238 | 249 | 320 | 447 | 607 | 786 |
| Influenza B | 13 | 17 | 24 | 45 | 64 | 140 |
| Influenza indeterminate | - | - | - | 1 | 10 | 4 |
| Influenza ungrouped | 4 | 6 | 10 | 18 | 16 | 23 |
| Legionella | ||||||
| Legionella longbeachae | 1 | 1 | - | - | - | - |
| Legionella other named | - | 1 | 1 | 2 | - | - |
| Legionella pneumophila | 10 | 8 | 14 | 7 | 8 | 7 |
| Legionella sp | 1 | - | 1 | 2 | 1 | 7 |
| Listeria | ||||||
| Listeria monocytogenes | 5 | 4 | 3 | 3 | 4 | 1 |
| Mycobacterium | ||||||
| Mycobacterium tuberculosis | 74 | 73 | 36 | 58 | 68 | 36 |
| Neisseria | ||||||
| Neisseria meningitidis | 15 | 13 | 5 | 9 | 11 | 10 |
| Orthopoxvirus | ||||||
| Monkeypox virus | 62 | 46 | 25 | 25 | 20 | 13 |
| Paramyxoviruses | ||||||
| Measles virus | 1 | 1 | 2 | 1 | - | 1 |
| Mumps virus | 1 | 11 | 2 | 50 | 5 | 1 |
| Plasmodium | ||||||
| Plasmodium falciparum | 2 | - | 2 | 12 | 9 | 3 |
| Plasmodium malariae | - | - | - | 1 | - | - |
| Plasmodium ovale | - | 1 | - | 1 | - | - |
| Plasmodium vivax | - | - | - | 1 | - | - |
| Polyomavirus | ||||||
| Polyomavirus BK | 23 | 40 | 46 | 52 | 38 | 55 |
| Polyomavirus JC | 3 | 5 | 3 | 8 | 5 | 12 |
| Rickettsia | ||||||
| Rickettsia spotted fever | - | - | - | 1 | - | - |
| Rubella virus | ||||||
| Rubella virus | 1 | 3 | 1 | 7 | 2 | 5 |
| Salmonella | ||||||
| Other salmonellas | 74 | 82 | 67 | 82 | 47 | 29 |
| Salmonella agona | 6 | - | - | - | 5 | - |
| Salmonella braenderup | 5 | - | - | - | - | - |
| Salmonella chester | 6 | - | - | 6 | - | - |
| Salmonella coeln | 5 | - | - | - | - | - |
| Salmonella enteritidis | 98 | 100 | 81 | 65 | 54 | 28 |
| Salmonella infantis | 11 | 5 | 9 | 8 | - | - |
| Salmonella java | 6 | - | - | - | - | - |
| Salmonella kentucky | 5 | - | 5 | 6 | - | - |
| Salmonella newport | - | 6 | 8 | - | 6 | - |
| Salmonella oranienburg | - | - | 6 | - | - | - |
| Salmonella saint-paul | 7 | - | 9 | - | - | - |
| Salmonella sp | 15 | 28 | 28 | 29 | 74 | 141 |
| Salmonella thompson | - | - | 5 | - | - | - |
| Salmonella typhi and paratyphi | 20 | 32 | 24 | 24 | 10 | 13 |
| Salmonella typhimurium | 71 | 48 | 70 | 65 | 43 | 13 |
| Salmonella virchow | 8 | 5 | 7 | 7 | - | - |
| Slmonella enterica | - | - | - | - | 5 | - |
| Shigella | ||||||
| Shigella boydii | - | 1 | 1 | 3 | - | - |
| Shigella dysenteriae | 1 | - | 1 | 1 | - | - |
| Shigella flexneri | 11 | 11 | 10 | 13 | 15 | 7 |
| Shigella sonnei | 22 | 24 | 16 | 27 | 16 | 29 |
| Shigella sp | 50 | 38 | 50 | 40 | 39 | 45 |
| Streptococcus | ||||||
| Streptococcus group A | 53 | 37 | 47 | 39 | 57 | 52 |
| Streptococcus pneumoniae | 46 | 49 | 55 | 81 | 93 | 93 |
| Vibrio | ||||||
| Vibrio cholerae | 1 | 1 | 1 | - | 2 | - |
Carbapenemase-producing Enterobacterales (CPE)*
Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2022/36 | 2022/37 | 2022/38 | 2022/39 | 2022/40 | 2022/41 | |
|---|---|---|---|---|---|---|---|
| Citrobacter | |||||||
| Citrobacter spp | IMP | - | - | - | - | 1 | - |
| KPC | - | 1 | 1 | 1 | - | - | |
| NDM | 1 | - | - | 1 | 1 | - | |
| OXA48 | - | 6 | 1 | - | 2 | - | |
| Enterobacter | |||||||
| Enterobacter cloacae complex | IMP | 1 | 1 | - | 1 | - | - |
| KPC | 5 | 7 | 3 | 4 | 2 | 1 | |
| NDM | 3 | - | - | - | 4 | 1 | |
| OXA48 | 2 | 2 | 2 | 1 | 1 | - | |
| Other | 1 | - | 1 | - | 1 | - | |
| Other enterobacter spp | KPC | 1 | - | - | - | 1 | - |
| Escherichia | |||||||
| Escherichia coli | IMP | - | 1 | - | 2 | - | - |
| KPC | 4 | 4 | 1 | 7 | 2 | 5 | |
| NDM | 6 | 2 | 11 | 10 | 6 | 1 | |
| OXA48 | 6 | 11 | 9 | 13 | 6 | 2 | |
| VIM | 1 | - | - | 1 | - | - | |
| Other | - | 1 | 1 | 2 | - | - | |
| Escherichia hermannii | KPC | - | - | - | - | 1 | - |
| NDM | - | - | 1 | - | - | - | |
| Klebsiella | |||||||
| Klebsiella oxytoca | IMP | - | - | 1 | - | 1 | - |
| KPC | 4 | 11 | 3 | 1 | 1 | - | |
| OXA48 | - | 1 | 1 | - | - | - | |
| Klebsiella pneumoniae | IMP | - | 3 | - | 1 | 1 | - |
| KPC | 6 | 4 | 9 | 5 | 7 | 4 | |
| NDM | 6 | 4 | 3 | 2 | 1 | - | |
| OXA48 | 10 | 2 | 7 | 8 | 8 | 1 | |
| VIM | - | - | 1 | - | - | - | |
| Other | - | 1 | 1 | 1 | 2 | - | |
| Other klebsiella spp | KPC | - | - | - | - | 1 | - |
| Leclercia | |||||||
| Leclercia adecarboxylata | KPC | - | - | - | - | 1 | - |
| Morganella | |||||||
| Morganella morganii | NDM | - | - | 1 | - | - | - |
| OXA48 | - | 2 | - | - | - | - | |
| Pantoea | |||||||
| Pantoea spp | OXA48 | 1 | - | - | - | - | - |
| Providencia | |||||||
| Providencia stuartii | VIM | - | - | 1 | - | - | - |
| Raoultella | |||||||
| Raoultella planticola (klebsiella planticola) | KPC | - | 1 | - | - | - | - |
| Shigella | |||||||
| Shigella spp | IMP | 1 | - | - | - | - | - |
Other carbapenemase-producing Gram-negative organisms*
Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2022/36 | 2022/37 | 2022/38 | 2022/39 | 2022/40 | 2022/41 | |
|---|---|---|---|---|---|---|---|
| Acinetobacter | |||||||
| Acinetobacter baumannii | Other | 1 | - | - | - | - | - |
| Pseudomonas | |||||||
| Pseudomonas aeruginosa | NDM | - | - | 1 | - | - | - |
| VIM | - | 1 | 1 | - | - | 1 | |
| Other | 3 | - | 1 | - | 4 | 1 | |
| Pseudomonas putida group | VIM | - | - | - | 1 | - | - |
| Other pseudomonas spp | Other | - | - | 1 | - | - | - |
*for all Carbapenemase-producing Gram-negative organisms, the reports are de- duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.