Research and analysis

NOIDs causative agents: week 37 (week ending 18 September 2022)

Updated 16 January 2023

NOIDs weekly report

Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia lamblia
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis D
  • Hepatitis E
  • Influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • Measles virus
  • Monkeypox virus
  • Mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium knowlesi
  • Plasmodium malariae
  • Plasmodium ovale
  • Plasmodium vivax
  • Polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2022/32 2022/33 2022/34 2022/35 2022/36 2022/37
Arboviruses            
West nile virus 1 - 1 - 1 -
Bacillus            
Bacillus cereus 27 40 31 20 31 14
Bordetella            
Bordetella pertussis - - 2 1 - -
Borrelia            
Borrelia burgdorferi 31 29 29 16 37 16
Borrelia sp 1 1 13 7 4 1
Borrelia tillae 2 1 2 - 5 1
Brucella            
Brucella melitensis - - 1 - - -
Burkholderia            
Burkholderia pseudomallei 1 - - - - -
Campylobacter            
Campylobacter coli 37 37 44 24 47 34
Campylobacter fetus - - - 1 - -
Campylobacter gracilis - - - 1 - -
Campylobacter helveticus - - - - 1 -
Campylobacter jejuni 298 275 271 247 276 194
Campylobacter lari 1 - - - - -
Campylobacter other named 1 - - - 1 -
Campylobacter sp 923 900 1,173 741 981 871
Campylobacter upsaliensis 2 - 1 1 2 1
Campylobacter ureolyticus (bacteroides corrodens) 2 - - 1 1 -
Chikungunya virus            
Chikungunya virus 2 - 2 - - 1
Clostridium            
Clostridium perfringens 41 32 23 15 24 11
Coronavirus            
Coronavirus 6 11 8 7 4 9
SARS-CoV-2 antibody indeterminate 63 50 80 35 98 144
SARS-CoV-2 antibody void 16 15 20 9 24 13
SARS-CoV-2 coronavirus (COVID-19) 39,311 29,829 26,147 25,567 24,999 28547
SARS-CoV-2 coronavirus (COVID-19) indeterminate 1,289 663 518 496 379 500
SARS-CoV-2 IgG antibody negative 376 316 412 276 332 457
SARS-CoV-2 IgG antibody positive 1,560 1,660 2,323 1,134 1,516 1698
SARS-CoV-2 IgM antibody negative - 2 - - 2 2
SARS-CoV-2 total antibody negative 551 498 590 305 408 514
SARS-CoV-2 total antibody positive 2,062 1,802 2,098 989 1,607 1,530
Corynebacterium            
Corynebacterium diphtheriae - 3 1 4 2 5
Corynebacterium ulcerans - - - 1 - 2
Coxiella            
Coxiella burnetii - - - 1 - -
Cryptosporidium            
Cryptosporidium cuniculus 1 - - - - -
Cryptosporidium hominis 10 13 24 50 53 8
Cryptosporidium parvum 38 26 64 38 40 35
Cryptosporidium sp 22 26 33 43 120 184
Cryptosporidium ubiquitum - 1 - 1 - -
Entamoeba            
Entamoeba histolytica 30 - 7 - 1 2
Escherichia            
Escherichia coli O 157 15 22 21 66 66 16
Flaviviruses            
Dengue virus 2 3 5 3 2 5
Giardia            
Giardia lamblia 2 2 2 1 - 1
Haemophilus            
Haemophilus influenzae 39 40 34 33 38 30
Hepatitis viruses            
Hepatitis A 16 14 13 16 17 16
Hepatitis B 177 172 158 159 175 136
Hepatitis C 389 372 490 195 504 346
Hepatitis D 3 1 3 2 2 7
Hepatitis E 26 26 23 20 30 30
Influenza virus            
Influenza A 147 125 148 181 238 236
Influenza B 19 16 16 14 12 17
Influenza ungrouped 5 - 8 2 4 6
Legionella            
Legionella longbeachae - - - - 1 -
Legionella other named - - - - - 1
Legionella pneumophila 4 6 2 9 10 6
Legionella sp - 5 - 5 1 1
Listeria            
Listeria monocytogenes 5 6 4 8 5 3
Mycobacterium            
Mycobacterium tuberculosis 61 61 91 68 64 56
Neisseria            
Neisseria meningitidis 7 11 6 6 15 12
Orthopoxvirus            
Monkeypox virus 171 107 88 67 62 43
Paramyxoviruses            
Measles virus 2 1 1 - 1 1
Mumps virus 1 1 1 2 1 8
Plasmodium            
Plasmodium falciparum 18 1 11 2 2 -
Plasmodium malariae 2 - 2 1 - -
Plasmodium ovale - - - - - 1
Polyomavirus            
Polyomavirus BK 41 27 35 37 23 40
Polyomavirus JC 2 3 3 3 3 5
Rickettsia            
Rickettsia spotted fever 1 1 - - - -
Rickettsia tsutsugamushi - 1 - - - -
Rubella virus            
Rubella virus 3 - 5 3 1 3
Salmonella            
Other salmonellas 84 82 74 64 60 29
Salmonella agona 5 - 5 - - -
Salmonella bovis-morbificans - 6 - - - -
Salmonella braenderup - - - 5 - -
Salmonella chester - - 5 - - -
Salmonella enteritidis 73 76 94 80 54 19
Salmonella infantis 8 9 7 8 8 -
Salmonella java - - - - 5 -
Salmonella mbandaka 7 - - - - -
Salmonella montevideo 5 - - - - -
Salmonella newport - - 8 9 - -
Salmonella oranienburg - 8 - 5 - -
Salmonella saint-paul - - - - 7 -
Salmonella sp 22 25 41 39 128 214
Salmonella typhi and paratyphi 6 10 19 17 19 18
Salmonella typhimurium 51 49 57 48 51 17
Salmonella virchow - 6 - 5 6 -
Slmonella enterica - 8 - - - -
Shigella            
Shigella boydii - 2 - - - -
Shigella dysenteriae - 1 1 1 1 -
Shigella flexneri 6 11 9 9 6 3
Shigella sonnei 11 18 19 15 20 13
Shigella sp 29 23 47 52 57 53
Streptococcus            
Streptococcus group A 73 61 74 54 53 35
Streptococcus pneumoniae 59 55 53 35 45 39
Vibrio            
Vibrio cholerae - 1 5 1 1 1

Carbapenemase-producing Enterobacterales (CPE)*

Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/32 2022/33 2022/34 2022/35 2022/36 2022/37
Citrobacter              
Citrobacter spp IMP - 1 - 1 - -
  KPC 2 2 2 - - -
  NDM - 2 - - 1 -
  OXA48 1 - 1 1 - -
Cronobacter              
Cronobacter sakazakii KPC - - - 1 - -
Other cronobacter spp KPC - 1 - - - -
Enterobacter              
Enterobacter cloacae complex IMP 4 3 3 2 1 -
  KPC 2 2 4 5 4 2
  NDM 2 3 1 2 2 -
  OXA48 2 1 1 1 1 -
  VIM 1 - - - - -
  Other - - - - 1 -
Other enterobacter spp IMP - - 1 - - -
  KPC - - - - 1 -
  NDM 1 - - - - -
  OXA48 - 2 2 1 - -
Escherichia              
Escherichia coli IMP 1 - 1 - - -
  KPC 5 8 1 7 1 -
  NDM 10 10 6 5 6 -
  OXA48 8 9 3 8 5 2
  VIM - - - - 1 -
  Other - - - 1 - -
Klebsiella              
Klebsiella other named KPC - - 1 - - -
Klebsiella oxytoca IMP 1 - - - - -
  KPC 2 6 1 - 4 7
Klebsiella oxytoca OXA48 - 1 2 - - -
  VIM - 1 - - - -
Klebsiella pneumoniae IMP 3 2 - - - -
  KPC 10 5 9 8 4 -
  NDM 6 5 4 2 6 1
  OXA48 7 4 13 11 8 2
  VIM 1 - 1 - - -
  Other 1 1 1 1 - -
Other klebsiella spp OXA48 - - - 1 - -
Kluyvera              
Kluyvera spp KPC 1 - - - - -
Mixta              
Mixta calida KPC - - - 1 - -
Pantoea              
Pantoea spp KPC - - - 1 - -
  OXA48 - - - - 1 -
  VIM - - - 1 - -
Serratia              
Serratia marcescens/ureilytica OXA48 - 1 - - - -

Other carbapenemase-producing Gram-negative organisms*

Please note: The numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/32 2022/33 2022/34 2022/35 2022/36 2022/37
Acinetobacter              
Acinetobacter baumannii IMP 1 3 - 1 - -
  NDM - 1 - - - -
  Other - - - - 1 -
Acinetobacter calcoaceticus/baumannii complex NDM 1 - - - - -
Pseudomonas              
Pseudomonas aeruginosa IMP 1 - - - - -
  NDM 1 1 1 - - -
  VIM - - 1 - - -
  Other 1 1 3 2 2 -

*for all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.