Research and analysis

NOIDs causative agents: week 11 (week ending 20 March 2022)

Updated 16 January 2023

NOIDs weekly report

Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:

  • Bacillus anthracis
  • Bacillus cereus
  • Bordetella pertussis
  • Borrelia spp
  • Brucella spp
  • Burkholderia mallei
  • Burkholderia pseudomallei
  • Campylobacter spp
  • Carbapenemase-producing Gram-negative bacteria
  • Chikungunya virus
  • Chlamydophila psittaci
  • Clostridium botulinum
  • Clostridium perfringens
  • Clostridium tetani
  • Corynebacterium diphtheriae
  • Corynebacterium ulcerans
  • Coxiella burnetii
  • Crimean-Congo haemorrhagic fever virus
  • Cryptosporidium spp
  • Dengue virus
  • Ebola virus
  • Entamoeba histolytica
  • Escherichia coli O 157
  • Francisella tularensis
  • Giardia lamblia
  • Guanarito virus
  • Haemophilus influenzae (invasive)
  • Hanta virus
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatitis D
  • Hepatitis E
  • Influenza virus
  • Junin virus
  • Kyasanur Forest disease virus
  • Lassa virus
  • Legionella spp
  • Leptospira interrogans
  • Listeria monocytogenes
  • Machupo virus
  • Marburg virus
  • Measles virus
  • Mumps virus
  • Mycobacterium tuberculosis complex
  • Neisseria meningitidis
  • Omsk haemorrhagic fever virus
  • Plasmodium falciparum
  • Plasmodium knowlesi
  • Plasmodium malariae
  • Plasmodium ovale
  • Plasmodium vivax
  • Polio virus
  • Rabies virus
  • Rickettsia spp
  • Rift Valley fever virus
  • Rubella virus
  • Sabia virus
  • Salmonella spp
  • SARS coronavirus
  • Shigella spp
  • Streptococcus group A (invasive)
  • Streptococcus pneumoniae (invasive)
  • Varicella zoster virus
  • Variola virus
  • Vibrio cholerae
  • West Nile virus
  • Yellow fever virus
  • Yersinia pestis

Statutory notifications of causative agents, grouped by root organism

Totals for the current week compared to the previous 5.

Week notification received 2022/07 2022/08 2022/09 2022/10 2022/11
Bacillus          
Bacillus cereus 15 17 17 14 19
Bordetella          
Bordetella pertussis - 1 1 2 4
Borrelia          
Borrelia burgdorferi 7 4 16 8 13
Borrelia sp - 2 2 1 2
Borrelia tillae - 1 - - 3
Burkholderia          
Burkholderia pseudomallei - - - - 1
Campylobacter          
Campylobacter coli 16 13 24 12 22
Campylobacter fetus - - 2 - 1
Campylobacter helveticus - - 1 - -
Campylobacter jejuni 231 213 265 234 226
Campylobacter lari - - 1 - -
Campylobacter rectus 1 - - - -
Campylobacter sp 706 679 709 631 561
Campylobacter upsaliensis 1 - - 1 1
Campylobacter ureolyticus (bacteroides corrodens) - - - - 2
Clostridium          
Clostridium perfringens 36 39 27 33 28
Coronavirus          
Coronavirus 104 33 41 50 58
Human coronavirus 229e 1 1 - 1 -
SARS coronavirus - - 1 - 2
SARS-CoV-2 antibody indeterminate 107 115 202 197 161
SARS-CoV-2 antibody void 49 46 53 912 50
SARS-CoV-2 coronavirus (COVID-19) 240,648 171,141 217,632 367,666 472,779
SARS-CoV-2 coronavirus (COVID-19) indeterminate 2,177 1,834 1,701 1,500 2,054
SARS-CoV-2 IgG antibody negative 5,004 1,149 1,336 1,325 1,304
SARS-CoV-2 IgG antibody positive 4,154 2,826 3,290 3,203 3,523
SARS-CoV-2 IgM antibody negative - 3 - 2 2
SARS-CoV-2 IgM antibody positive 1 2 - - 3
SARS-CoV-2 total antibody negative 3,062 5,720 1,417 7,817 1841
SARS-CoV-2 total antibody positive 6,458 10,287 4,337 15,467 5,219
Corynebacterium          
Corynebacterium diphtheriae - - 2 - -
Corynebacterium ulcerans - - - 3 -
Coxiella          
Coxiella burnetii - - 1 - -
Cryptosporidium          
Cryptosporidium felis 1 - - - -
Cryptosporidium hominis - - 1 - -
Cryptosporidium parvum 12 15 14 16 15
Cryptosporidium sp 13 19 18 27 21
Entamoeba          
Entamoeba histolytica - - 1 2 -
Escherichia          
Escherichia coli O 157 4 2 2 4 4
Flaviviruses          
Dengue virus - 1 - - 1
Haemophilus          
Haemophilus influenzae 55 39 41 40 34
Hepatitis viruses          
Hepatitis A 17 8 9 7 6
Hepatitis B 157 132 133 143 155
Hepatitis C 349 325 233 343 380
Hepatitis D 6 3 - 2 -
Hepatitis E 21 24 21 20 18
Influenza virus          
Influenza A 203 250 283 414 665
Influenza B 37 32 17 20 132
Influenza indeterminate - 6 - 4 -
Influenza ungrouped - 1 2 - 5
Legionella          
Legionella pneumophila 6 5 - - 1
Legionella sp - - 1 1 -
Listeria          
Listeria monocytogenes 5 1 - 2 9
Mycobacterium          
Mycobacterium tuberculosis 50 58 60 48 48
Neisseria          
Neisseria meningitidis 5 6 9 6 9
Paramyxoviruses          
Measles virus 1 - 1 1 -
Mumps virus - - - 2 2
Plasmodium          
Plasmodium falciparum - 2 - - -
Polyomavirus          
Polyomavirus BK 34 23 32 24 23
Polyomavirus JC 4 4 3 5 4
Rubella virus          
Rubella virus 4 4 1 5 2
Salmonella          
Other salmonellas 40 40 38 23 25
Salmonella enteritidis 14 7 22 20 7
Salmonella mbandaka - 6 - - -
Salmonella newport 7 - 6 - -
Salmonella sp 6 11 5 18 65
Salmonella typhi and paratyphi 10 6 14 6 8
Salmonella typhimurium 31 23 40 23 25
Shigella          
Shigella boydii - 3 1 2 -
Shigella dysenteriae - - - - 1
Shigella flexneri 11 10 19 12 17
Shigella sonnei 16 17 12 10 5
Shigella sp 40 32 31 32 35
Streptococcus          
Streptococcus group A 21 32 22 33 24
Streptococcus pneumoniae 80 62 73 72 71
Vibrio          
Vibrio cholerae - - 1 - 1

Carbapenemase-producing Enterobacterales (CPE)[footnote 1]

Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/07 2022/08 2022/09 2022/10 2022/11
Citrobacter            
Citrobacter spp KPC 1 - - - -
  OXA48 2 - - - -
Enterobacter            
Enterobacter cloacae complex IMP 1 - - - -
  KPC 1 2 2 2 -
  NDM - 3 - - -
  OXA48 - - 1 - -
  Other - 1 - - -
Escherichia            
Escherichia coli KPC 1 5 4 3 1
  NDM 1 1 2 1 -
  OXA48 2 2 3 2 3
  Other - - - 2 -
Klebsiella            
Klebsiella oxytoca KPC - 1 3 1 -
  OXA48 1 1 - - -
Klebsiella pneumoniae KPC 3 5 6 3 1
  NDM 3 1 4 1 1
  OXA48 5 2 4 7 4
  Other 1 - 2 - -
Klebsiella variicola KPC - - - 1 -
Morganella            
Morganella morganii OXA48 - - 1 - -

Other carbapenemase-producing Gram-negative organisms[footnote 1]

Please note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.

Week notification received 2022/07 2022/08 2022/09 2022/10 2022/11
Pseudomonas            
Pseudomonas aeruginosa VIM - - - - 1
  Other - 1 1 1 -
  1. For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.  2