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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 that have a primary purpose of translational and applied research - other human disorders, including:
gastrointestinal disorders including liver
The following projects were granted:
gene transfer to small animals (gene therapy, genetic disease)
development of assays to quantify gluten content in gluten-free foods (coeliac disease, gluten, monoclonal antibodies)
zebrafish as a model of inherited renal disease (cystic kidney, cilial, treatment, pronephros)
immunology studies to support drug discovery (immunology, inflammation)
genetic models to study inflammatory diseases (inflammation, arthritis, infection, PAR-2, MKP-2)
interventions against chlamydia (chlamydia, macaque, vaccine, efficacy, immunogenicity)
mechanisms and treatments of renal transplant-related injury in mouse models (ischemia/reperfusion (I/R) injury, immunosuppressant-cyclosporine A (CsA), erythropoietin (EPO) derived new cyclic helix B surface peptide (CHBP), caspase-3 small interfering RNA (siRNA) and genetic modified mice)
finding treatments for chronic kidney disease (kidney, fibrosis, CKD)