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Non-tech. summaries 2014: projects on human cancer

Projects granted during 2014 that have a primary purpose of translational and applied research: human cancer.


Non-technical summaries: projects granted in 2014, volume 11

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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2014 with a primary purpose of translational and applied research: human cancer.

The following projects were granted:

  • radiosensitisation of bladder tumours and normal tissues (bladder cancer, radiotherapy, radiosensitisation, normal tissue effects, orthotopic bladder model)

  • using mechanical stimuli to move therapies into tumours and vaccines across the skin (tumour, vaccine, mechanical, delivery, ultrasound)

  • virus based therapies in preclinical cancer models (adenovirus, cancer, oncolytic)

  • in-house service production monoclonal antibodies (monoclonal antibodies, infections, disease, diagnostics, vaccination)

  • engineering immunity to cancer (genetic modification, T-cells, cancer, therapy)

  • the isolation of novel antibody therapeutics for the treatment of human disease (antibody, cartilaginous fish, therapeutic drug)

  • molecular basis and theory of gynaecological cancer (ovarian cancer, gynaecological cancer, immunotherapy, chemotherapy)

  • developing selective, novel cancer therapeutics (cancer, drug discovery, therapeutics, preclinical)

  • targeting cancer stem cells and their micro environment (cancer stem cells, pancreatic cancer)

  • imaging in drug discovery (non-invasive, medical imaging, drug discovery)

  • the cause of resistance to treatment in human blood cancers (blood cancers, resistance, genome-damage)

  • experimental cancer diagnosis and therapy (cancer, tumour, diagnosis, therapy, models)

  • protecting stem cell and tissue function (stem cells, ageing, drug development, regeneration, mucositis)

  • nanomedicine based drug delivery (nanotechnology, drug development, brain diseases, biologics)

  • development of novel agents for cancer therapy (cancer, novel drugs)

  • development of personalised anti-cancer strategies (cancer, drugs, translation, biomarkers, metastasis)

  • micro environment signalling in cancer (cancer, micro environment, therapy)

  • novel multifunctional phage for guided systemic cancer gene therapy

  • evaluation of anti-cancer drugs (cancer, drugs)

  • epithelial-stromal interaction in cancer (cancer, stroma, epithelium, breast, lung)

  • biology of relapsed childhood leukaemia (leukaemia, drug-resistance, relapse, bone marrow micro environment)

  • immunisation of rodents (immunise antigens antibodies)

Published 25 April 2016