Research and analysis

COVID-19 confirmed deaths in England (to 31 December 2021): report

Updated 28 April 2023

COVID-19 deaths

UK Health Security Agency (UKHSA), formerly Public Health England (PHE), has published statistics on deaths in people with laboratory-confirmed coronavirus (COVID-19) since 29 April 2020. In this report we present the latest data on COVID-19 mortality. Read more information on the data series.

Data sources

Cases of laboratory diagnosed COVID-19 resident in England were identified from the Second Generation Surveillance System (SGSS).

Fact and date of death were derived from combined sources: NHS England hospital deaths, Office for National Statistics (ONS) death registrations, UKHSA Health Protection Team direct reporting and Demographic Batch Service tracing of laboratory-confirmed cases.

Definitions

In this report deaths are defined as a death in a person with a laboratory-confirmed positive COVID-19 test and either:

  • died within 60 days of the first specimen date, or
  • died more than 60 days after the first specimen date with COVID-19 mentioned on the death certificate

This data does not include deaths in people where COVID-19 is suspected but not confirmed by testing (SARS-CoV-2 PCR either negative or not tested).

This data does not report cause of death, and as such represents all deaths in people with laboratory-confirmed COVID-19, not just those caused by COVID-19.

In this report, data is reported from 1 January 2021 to 31 December 2021.

Mortality rates are calculated using 2020 ONS population estimates data.

Age-standardised rates adjust for differences in the age structure of populations. The standard used throughout this report is the European Standard Population 2013.

Methods

Mortality rates presented for different time periods have been annualised in order to enable comparisons. This method involves adjusting the population data used to calculate rates for the time period covered, these are expressed as mortality rates per 100,000 population per year.

These rates cannot be compared with rates that do not have this adjustment.

Mortality rates by region, local authority, sex, ethnic group and Index of Multiple Deprivation (IMD) have been age-standardised to account for the different age distributions within different populations.

All figures displaying mortality rates have been calculated using a 7-day rolling average, to allow for smoothing of fluctuating data.

COVID-19 mortality rates

Within the period 1 January 2021 to 31 December 2021, 9,051,681 cases of COVID-19 were detected in England.

In the same period, there have been 78,128 deaths in persons with laboratory-confirmed COVID-19. This represents a crude mortality rate of 138 per 100,000 population. From 1 January 2021 onwards, the highest recorded number of daily deaths was 1,364 deaths on 19 January 2021.

Table 1. Number of laboratory-confirmed cases, deaths and crude mortality rate (per 100,000 population) in laboratory-confirmed cases of COVID-19, by month*†

Cases Deaths Crude mortality rate (95% CI)
Jan-21 1,080,364 33,341 59.0 (58.3 - 59.6)
Feb-21 292,738 16,508 29.2 (28.7 - 29.6)
Mar-21 136,152 5,224 9.2 (9.0 - 9.5)
Apr-21 59,665 1,329 2.4 (2.2 - 2.5)
May-21 61,954 509 0.9 (0.8 - 1.0)
Jun-21 297,040 472 0.8 (0.8 - 0.9)
Jul-21 936,381 1,607 2.8 (2.7 - 3.0)
Aug-21 784,839 3,102 5.5 (5.3 - 5.7)
Sep-21 764,583 3,724 6.6 (6.4 - 6.8)
Oct-21 1,052,671 4,007 7.1 (6.9 - 7.3)
Nov-21 1,005,172 4,192 7.4 (7.2 - 7.6)
Dec-21 2,580,122 4,113 7.3 (7.1 - 7.5)

*Data is presented from 1 January 2021 to 31 December 2021. Due to continuous data quality improvements, reported number of cases and deaths may be subject to fluctuations. These numbers represent a snapshot of the number of cases and deaths at the time of report production.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 1. Number of deaths in laboratory-confirmed cases of COVID-19 by date of death, from 1 January 2021 to 31 December 2021*†

*Data is presented from 1 January 2021 to 31 December 2021.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Age and sex distribution

Since 1 January 2021, the mortality rate was highest among those aged over 80 (annualised rate of 1,493 per 100,000 population per year).

Table 2. Number of deaths and annualised mortality rate** (per 100,000 population per year) in laboratory-confirmed cases of COVID-19, by age group†

Age Deaths (1 January 2021 to 31 December 2021*) Mortality rate** (95% CI) (1 January 2021 to 31 December 2021*) Deaths (December 2021) Mortality rate ** (95% CI) (December 2021)
<5 18 0.6 (0.3 - 0.9) <10 1.1 (0.2 - 3.2)
5 - 9 <10 0.2 (0.1 - 0.4) <10 0.3 (0.0 - 1.9)
10 - 19 67 1.0 (0.8 - 1.3) 11 2.0 (1.0 - 3.5)
20 -29 225 3.1 (2.7 - 3.5) 21 3.4 (2.1 - 5.2)
30 - 39 727 9.6 (8.9 - 10.3) 79 12.3 (9.7 - 15.3)
40 - 49 1,841 25.9 (24.7 - 27.1) 149 24.7 (20.9 - 28.9)
50 - 59 4,930 64.6 (62.8 - 66.4) 345 53.2 (47.7 - 59.1)
60 - 69 9,719 162.5 (159.3 - 165.8) 621 122.2 (112.8 - 132.3)
70 - 79 17,949 372.1 (366.6 - 377.6) 944 230.4 (215.9 - 245.6)
80+ 42,643 1493.3 (1479.2 - 1507.6) 1,939 799.5 (764.3 - 835.9)

Note: Numbers of deaths fewer than 10 have been excluded to minimise the risk of deductive disclosure.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

From 1 January 2021 to 31 December 2021, 42,028 (annualised rate of 172.5 per 100,000 population per year) deaths have occurred in males and 36,097 (116.1 per 100,000 per year) in females. The mortality rate in both sexes in December was considerably lower than the average for the total period 1 January 2021 to 31 December 2021.

Table 3. Number of deaths and age-adjusted annualised mortality rate ** (per 100,000 population) in laboratory-confirmed cases of COVID-19, by sex†

Sex Deaths (1 January 2021 to 31 December 2021) Age-adjusted mortality rate** (95% CI) (1 January 2021 to 31 December 2021) Deaths (December 2021) Age-adjusted mortality rate** (95% CI) (December 2021)
Female 36,097 116.1 (114.9 - 117.3) 1,820 6.0 (5.7 - 6.3)
Male 42,028 172.5 (170.8 - 174.1) 2,293 9.3 (9.0 - 9.7)

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 2.a. Seven-day rolling average annualised mortality rates** (per 100,000 population per year) in laboratory-confirmed cases of COVID-19 by age group, from 1 January 2021 to 31 December 2021*†

*Data is presented from 1 January 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 2.b. Seven-day rolling average annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by age group, December 2021*†

*Data is presented from 1 December 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Ethnicity

Overall, the age-adjusted annualised mortality rate from 1 January 2021 onwards was highest among those of Black or Black British ethnic groups (annualised rate of 296.4 per 100,000 population per year) followed by those Asian or Asian British ethnic groups (annualised rate of 294.4 per 100,000 population per year).

Table 4. Number of deaths and age-adjusted annualised mortality rate* (per 100,000 population) in laboratory-confirmed cases of COVID-19, by ethnicity**†

Ethnic group Deaths (1 January 2021 to 31 December 2021*) Age-adjusted mortality rate** (95% CI) (1 January 2021 to 31 December 2021*) Deaths (December 2021) Age-adjusted mortality rate** (95% CI) (December 2021)
White 67,038 133.5 (132.5 - 134.5) 3,440 6.9 (6.7 - 7.2)
Black / Black British 2,640 296.4 (284.4 - 308.7) 171 19.2 (16.3 - 22.5)
Asian / Asian British 5,649 294.4 (286.3 - 302.6) 246 13.0 (11.4 - 14.8)
Mixed / Multiple ethnic groups 433 148.4 (133.3 - 164.5) 30 9.7 (6.2 - 14.3)
Other 480 223.3 (201.9 - 246.0) 27 12.8 (8.0 - 19.0)

*Rates are annualised and expressed as the number of deaths per 100,000 population per year.

**Ethnic categories are based on ONS classifications.

±The rates in the Other ethnic group are likely to be an overestimate due to the difference in the method of allocating ethnicity codes to the deaths data and the population data used to calculate the rates.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 3.a. Seven-day rolling average age-adjusted annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by ethnicity***±, 1 January 2021 to 31 December 2021†

*Data is presented from 1 January 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

***Ethnic categories are based on ONS classifications.

±The rates in the Other ethnic group are likely to be an overestimate due to the difference in the method of allocating ethnicity codes to the cases data and the population data used to calculate the rates.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 3.b. Seven-day rolling average age-adjusted mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by ethnicity***±, December 2021†

*Data is presented from 1 December 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

±The rates in the Other ethnic group are likely to be an overestimate due to the difference in the method of allocating ethnicity codes to the cases data and the population data used to calculate the rates.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Deprivation

Relative deprivation was assessed using quintiles of the IMD linked to residential lower super output area, with IMD 1 representing the most deprived. Overall, from 1 January 2021, the age-adjusted annualised mortality rate is highest among those living in the most deprived areas, with a gradual decrease in mortality rate seen with decreasing deprivation.

In December 2021, the age-adjusted annualised mortality rate is highest among those living in areas of the most deprived quintile, IMD quintile 1, and the lowest mortality rate is seen among those in the least deprived quintile, quintile 5.

Table 5. Number of deaths and age-adjusted annualised mortality rate** (per 100,000 population) in laboratory-confirmed cases of COVID-19, by IMD quintile†

IMD Quintile (1 most deprived) Deaths (1 January 2021 to 31 December 2021*) Age-adjusted mortality rate** (95% CI) (1 January 2021 to 31 December 2021*) Deaths (December 2021) Age-adjusted mortality rate** (95% CI) (December 2021)
1 18,006 220.7
(217.4 - 223.9)
1,061 12.8 (12.0 - 13.5)
2 16,682 171.9
(169.3 - 174.5)
922 9.5 (8.9 - 10.1)
3 15,463 133.9
(131.8 - 136.1)
745 6.5 (6.0 - 7.0)
4 14,460 116.0
(114.1 - 117.9)
696 5.6 (5.2 - 6.1)
5 13,072 100.6
(98.9 - 102.4)
634 5.0 (4.6 - 5.4)

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 4.a. Seven-day rolling average age-adjusted annualised mortality rate** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by IMD quintile, 1 January 2021 to 31 December 2021*†

*Data is presented from 1 January 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 4.b. Seven-day rolling average age-adjusted annualised mortality rate** (per 100,000) population in laboratory-confirmed cases of COVID-19 by IMD quintile, December 2021*†

*Data is presented from 1 December 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Regional breakdown

Since 1 January 2021, the annualised mortality rate was highest in London (176.7 per 100,000 population per year), followed by the West Midlands (157.6 per 100,000 population per year) and East of England (155.3 per 100,000 population per year).

The lowest mortality rate was seen in the South West (88.6 per 100,000 population per year). In December 2021, the highest annualised mortality rate was seen in London (9.6 per 100,000 population per year).

Table 6. Number of deaths and age-adjusted annualised mortality rate** (per 100,000 population) in laboratory-confirmed cases of COVID-19, by UKHSA centre†

UKHSA centre Deaths (1 January 2021 to 31 December 2021*) Age-adjusted mortality rate** (95% CI) (1 January 2021 to 31 December 2021*) Deaths (December 2021) Age-adjusted mortality rate** (95% CI) (December 2021)
East Midlands 7,100 144.9
(141.6 - 148.4)
429 8.8 (8.0 - 9.6)
East of England 10,627 155.3
(152.4 - 158.3)
438 6.5 (5.9 - 7.1)
London 10,731 176.7
(173.3 - 180.1)
586 9.6 (8.8 - 10.4)
North East 3,748 136.0
(131.6 - 140.4)
229 8.4 (7.3 - 9.5)
North West 10,991 153.0
(150.2 - 155.9)
613 8.5 (7.9 - 9.2)
South East 12,578 132.0
(129.7 - 134.3)
528 5.7 (5.2 - 6.2)
South West 5,905 88.6
(86.3 - 90.9)
392 6.0 (5.4 - 6.6)
West Midlands 9,220 157.6
(154.4 - 160.9)
430 7.4 (6.8 - 8.2)
Yorkshire and Humber 6,783 125.0
(122.0 - 128.0)
413 7.6 (6.9 - 8.4

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 5.a. Seven-day rolling average age-adjusted annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by UKHSA centre, 1 January 2021 to 31 December 2021*†

*Data is presented from 1 January 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 5.b. Seven-day rolling average age-adjusted annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by UKHSA centre, December 2021*†

*Data is presented from 1 December 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 6.a. Age-adjusted annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19 by upper-tier local authority, 1 January 2021 to 31 December 2021*†

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figure 6.b. Age-adjusted annualised mortality rates** (per 100,000 population) in laboratory-confirmed cases of COVID-19, by upper-tier local authority, December 2021*†

*Data is presented from 1 December 2021 to 31 December 2021.

**Rates are annualised and expressed as the number of deaths per 100,000 population per year.

†Deaths within 60 days of a positive COVID-19 test or where COVID-19 is mentioned on the death certificate.

Figures 6a and 6b:

  • contain Ordnance Survey data © Crown copyright and database right 2020
  • contain National Statistics data © Crown copyright and database right 2020

Case fatality risk

Case fatality risk (CFR) describes the risk of death following a laboratory-confirmed positive COVID-19 test. For this report, CFR has been calculated within 60 days of an individual’s first positive specimen (from PCR, LAMP, and LFD tests) CFR is reported on data 1 January 2021 up to and including 12 November 2021.

Cases diagnosed in the last 60 days were excluded from this analysis, due to incomplete follow-up period. Deaths are excluded from the CFR calculation if they cannot be linked to laboratory-confirmed COVID-19 case data.

CFR is sensitive to:

  • changes in testing coverage and detection rate of COVID-19 infections (Dudel and others, 2020; Wu and others, 2020; Harman and others, 2021)
  • changes in the demographics of the infected population
  • changes in the effectiveness of treatment and the health system’s ability to care for severe COVID-19 cases

Table 7. Number of laboratory-confirmed cases, deaths and case fatality risk in laboratory-confirmed cases of COVID-19, 1 January 2021 to 12 November 2021*†

Cases Deaths† Case fatality risk (%)
1 January 2021 to 12 November 2021 5,825,120 57,879 1.0

*Figures differ from Table 1 based on CFR calculation inclusion criteria.

†Deaths within 60 days of a positive COVID-19 test and linked to the confirmed COVID-19 case data.

Figure 7. Number of laboratory-confirmed cases, deaths and case fatality risk in laboratory-confirmed cases of COVID-19, 1 January 2021 to 12 November 2021*†

Note: The time period presented covers a period where testing coverage and testing modes have changed significantly, therefore apparent changes in estimated case fatality should be interpreted with caution.

Numbers of cases and deaths are stacked by week. Cases are presented by week of specimen date. Deaths are presented by week of death.

*Data presented from 1 January 2021 to 12 November 2021, the last full week of full data available.

†Deaths within 60 days of a positive COVID-19 test and linked to the confirmed COVID-19 case data.

Report prepared by UKHSA COVID-19 Epidemiology Cell