Guidance

Antimicrobial intravenous-to-oral switch: criteria for prompt switch

National antimicrobial intravenous-to-oral switch (IVOS) criteria for prompt switch​ have been developed for adult and paediatric patients, categorised into 5 sections.

Documents

Antimicrobial IVOS decision aid for adults

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Details

In 2022, the IVOS criteria for adults were developed through collation of criteria from a sample of 45 acute hospital IVOS policies, completion of a rapid systematic literature review to validate selection of criteria, and a 4-step Delphi consensus-gathering process involving 279 multidisciplinary participants from all UK nations to agree evidence-based, UK-wide IVOS criteria for hospitalised adult patients.

In 2024, paediatric IVOS criteria were also developed. The 29 criteria were co-produced through a UK-wide consensus process involving 170 multidisciplinary participants.

These projects were led by the UK Health Security Agency (UKHSA)’s Healthcare-Associated Infection, Fungal, Antimicrobial Resistance, Antimicrobial Use and Sepsis Division, in collaboration with NHS England AMR Programme and UKHSA’s Behavioural Science and Insights Unit. 

Published 1 November 2022
Last updated 4 April 2024 + show all updates
  1. Added paediatric IVOS prompt early switch criteria. Changed attachment titles to specify for adult patients.

  2. Added IVOS decision aid.

  3. First published.