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Annex B to TOX 2026/32

Published 4 September 2026

This is a paper for discussion. This does not represent the views of the Committee and should not be cited.

Table 1. Summary of food groups and occurrence data used for exposure assessment (Kuhlne et al, 2008a; 2008b; 2009a; 2009b)

Food group Subgroup Total Phytoestrogens (µg/kg) Total Isoflavones (µg/kg)
Coffee Coffee, instant powder 18330 9130
Coffee Coffee, infusion1 170* <10*
Nuts and seeds Almonds (incl nut butter) 1120 <1000
Nuts and seeds Brazil nuts 8870 1050
Nuts and seeds Cashews (incl nut butter) 1820 <1000
Nuts and seeds Peanuts (incl nut butter) 4270 1540
Nuts and seeds Pine nuts 1030 <1000
Nuts and seeds Walnuts 1750 <1000
Nuts and seeds Pumpkins seeds 5390 <1000
Nuts and seeds Sunflower seeds 1110 <1000
Soya based alternatives to milk Soy drink (milk) -unflavoured, unsweetened, fortified etc2 93130 93070
Soya based alternatives to dairy products Yogurt, soy2 82860 82350
Soya based alternatives to dairy products Soy ice cream2 134940 134880
Soy based meat substitutes Burger, soy based2 44490 44150
Soy based meat substitutes Mince, savory, soy or TVP based (high soy content)2 287580 286180
Soy based meat substitutes Sausage, TVP/ soy2 39940 39460
Soy based meat substitutes Soya bean, Tofu 106190 106090
Soy based meat substitutes Bread, white 6810 6750
  1. A value below the 1000 µg/kg cut off was used for exposure assessment to distinguish between consumption of instant coffee powder and a coffee infusion.
  2. Proxy data or partial proxy data used.
  3. Conversion factor applied to raw/ dry foods to convert to cooked/ wet weight food.

Table 2. Acute exposure to total phytoestrogens from food for women of childbearing age (16-49 years)

Food group Subgroup Mean (µg/person) 97.5th percentile (µg/person) Mean (µg/kg bw) 97.5th percentile (µg/kg bw)
Coffee Coffee, instant powder 49 150 0.71 2.1
Coffee Coffee, infusion1 36 140 0.53 1.9
Nuts and seeds Almonds (incl nut butter) 8.2 41 0.12 0.69
Nuts and seeds Brazil nuts 56 220 0.85 3.4
Nuts and seeds Cashews (incl nut butter) 15 88 0.24 1.4
Nuts and seeds Peanuts (incl nut butter) 95 350 1.4 5.4
Nuts and seeds Pine nuts 3.0 17 0.046 0.31
Nuts and seeds Walnuts 11 44 0.17 0.67
Nuts and seeds Pumpkins seeds 46 210 0.71 3.3
Nuts and seeds Sunflower seeds 7.3 47 0.11 0.83
Soya based alternatives to milk Soy (drink) milk -unflavoured, unsweetened, fortified etc2 24000 65000 360 1100
Soya based alternatives to dairy products Yogurt, soy2 8500 23000 120 330
Soya based alternatives to dairy products Soy ice cream2 11000 24000 160 410
  1. A value below threshold was used to distinguish between consumption of instant coffee powder and a coffee infusion.
  2. Proxy data or partial proxy data used.
  3. Conversion factor applied to raw/ dry foods to convert to cooked/ wet weight food.or vice versa.
  4. This exposure is based on limited data in NDNS for soya-linseed bread food codes. Additional explanation above the table and in the appendix.
  5. Consumption or exposure estimates made with a small number of consumers may not be accurate. The number of consumers is less than 60, this should be treated with caution and may not be representative for a large number of consumers.
  6. The food group has been provided for information only to compare with the soya/ linseed bread group and has not been included in the all food group estimates.

Table 3. Acute exposure to isoflavones from food for women of childbearing age (16-49 years)

Food group Subgroup Mean (µg/person) 97.5th percentile (µg/person) Mean (µg/kg bw) 97.5th percentile (µg/kg bw)
Coffee Coffee, instant powder 25 73 0.36 1.1
Coffee Coffee, infusion1 2.1 8.3 0.031 0.11
Nuts and seeds Brazil nuts 6.6 26 0.10 0.4
Nuts and seeds Peanuts (incl nut butter) 34 130 0.51 1.9
Soya based alternatives to milk Soy (drink) milk -unflavoured, unsweetened, fortified etc2 24000 65000 360 1100
Soya based alternatives to dairy products Yogurt, soy2 8400 23000 120 330
Soya based alternatives to dairy products Soy ice cream2 11000 24000 160 410
Soy based meat substitutes Burger, soy based2 3200 7900 46 110
Soy based meat substitutes Mince, savory, soy or TVP based (high soy content)2 25000 59000 360 900
Soy based meat substitutes Sausage, TVP/ soy2 3600 7800 52 130
Soy based meat substitutes Soya bean, Tofu5 9200 21000 140 460
Bread (excl. soya/ linseed bread) Bread, white 690 1500 10 25
Bread (excl. soya/ linseed bread) Bread, brown/ wholemeal 460 1100 6.7 16
Bread (excl. soya/ linseed bread) Bread, granary mixed grain, wheatgerm2 630 1300 9.4 22
Bread, soya/ linseed bread Bread, soya—linseed 4,5 86004 200004 1304 2604
Bread, soya/ linseed bread Bread, soya and linseed bread plus other bread2,6 9000 19000 130 310
Legumes Green beans (including runner beans and French beans3 92 330 1.3 4.8
Legumes Beansprouts 98 340 1.5 5.0
Legumes Chickpeas3 160 660 2.6 9.9
Legumes Soya beans3 670 6900 10 93
Legumes Soya flour 810 3300 12 55
All food groups All 31000 81000 460 1300
  1. A value below threshold was used to distinguish between consumption of instant coffee powder and a coffee infusion.
  2. Proxy data or partial proxy data used.
  3. Conversion factor applied to raw/ dry foods to convert to cooked/ wet weight food.or vice versa.
  4. This exposure is based on limited data in NDNS for soya-linseed bread food codes. Additional explanation above the table and in the appendix.
  5. Consumption or exposure estimates made with a small number of consumers may not be accurate. The number of consumers is less than 60, this should be treated with caution and may not be representative for a large number of consumers.
  6. The food group has been provided for information only to compare with the soya/ linseed bread group and has not been included in the all food group estimates.

Table 4. Chronic exposure to total phytoestrogens from food for women of childbearing age (16-49 years)

Food group Subgroup Mean (µg/day) 97.5th percentile (µg/day) Mean (µg/kg bw/day) 97.5th percentile (µg/kg bw/day)
Coffee Coffee, instant powder 32 110 0.46 1.6
Coffee Coffee, infusion1 18 81 0.26 1.2
Nuts and seeds Almonds (incl nut butter) 2.8 16 0.042 0.22
Nuts and seeds Brazil nuts 20 87 0.31 1.5
Nuts and seeds Cashews (incl nut butter) 5.1 34 0.079 0.48
Nuts and seeds Peanuts (incl nut butter) 30 120 0.45 1.8
Nuts and seeds Pine nuts 0.84 5.0 0.013 0.086
Nuts and seeds Walnuts 4.1 20 0.063 0.30
Nuts and seeds Pumpkins seeds 17 67 0.27 0.97
Nuts and seeds Sunflower seeds 3.2 22 0.048 0.31
Soya based alternatives to milk Soy (drink) milk - unflavoured, 14000 43000 210 680
  1. A value below threshold was used to distinguish between consumption of instant coffee powder and a coffee infusion.
  2. Proxy data or partial proxy data used.
  3. Conversion factor applied to raw/ dry foods to convert to cooked/ wet weight food.or vice versa.
  4. This exposure is based on limited data in NDNS for soya-linseed bread food codes. Additional explanation above the table and in the appendix.
  5. Consumption or exposure estimates made with a small number of consumers may not be accurate. The number of consumers is less than 60, this should be treated with caution and may not be representative for a large number of consumers.
  6. The food group has been provided for information only to compare with the soya/ linseed bread group and has not been included in the all food group estimates.

Table 5. Chronic exposure to isoflavones from food for women of childbearing age (16-49 years)

Food group Subgroup Mean (µg/day) 97.5th percentile (µg/day) Mean (µg/kg bw/day) 97.5th percentile (µg/kg bw/day)
Coffee Coffee, instant powder 16 55 0.23 0.78
Coffee Coffee, infusion1 1.1 4.8 0.016 0.070
Nuts and seeds Brazil nuts 2.4 10 0.037 0.18
Nuts and seeds Peanuts (incl nut butter) 11 43 0.16 0.64
Soya based alternatives to milk Soy (drink) milk -unflavoured, unsweetened, fortified etc2 14000 43000 210 680
Soya based alternatives to dairy products Yogurt, soy2 3200 11000 47 170
Soya based alternatives to dairy products Soy ice cream2 3200 9100 48 140
Soy based meat substitutes Burger, soy based2 880 2200 13 36
Soy based meat substitutes Mince, savory, soy or TVP based (high soy content)2 7500 23000 110 340
Soy based meat substitutes Sausage, TVP/ soy2 1100 2800 15 43
Soy based meat substitutes Soya bean, Tofu5 2800 7000 44 150
Bread (excl. soya/ linseed bread) Bread, white 310 880 4.6 14
Bread (excl. soya/ linseed bread) Bread, brown/ wholemeal 210 590 3.0 9.0
Bread (excl. soya/ linseed bread) Bread, granary mixed grain, wheatgerm2 260 780 3.9 12
Bread, soya/ linseed bread Bread, soya—linseed4,5 35004 94004 494 1304
Bread, soya/ linseed bread Bread, soya and linseed bread plus other bread 2,6 3700 11000 56 170
Legumes Green beans (including runner beans and French beans3 26 87 0.38 1.4
Legumes Beansprouts 27 96 0.41 1.5
Legumes Chickpeas3 58 290 0.90 4.9
Legumes Soya beans3 200 1800 3.0 30
Legumes Soya flour 270 1000 3.9 18
All food groups All 18000 49000 260 780
  1. A value below threshold was used to distinguish between consumption of instant coffee powder and a coffee infusion.
  2. Proxy data or partial proxy data used.
  3. Conversion factor applied to raw/ dry foods to convert to cooked/ wet weight food.or vice versa.
  4. This exposure is based on limited data in NDNS for soya-linseed bread food codes. Additional explanation above the table and in the appendix.
  5. Consumption or exposure estimates made with a small number of consumers may not be accurate. The number of consumers is less than 60, this should be treated with caution and may not be representative for a large number of consumers.
  6. The food group has been provided for information only to compare with the soya/ linseed bread group and has not been included in the all food group estimates.