Highways England contractors will be resurfacing sections of the eastbound carriageway between 8pm and 6am when work starts on Monday 16 November.
Highways England project manager Tim Calvert said:
This is essential maintenance work that, once complete, will provide drivers with a safer and smoother journey.
To keep disruption to a minimum, this work will be carried out between 8pm and 6am when traffic levels are lower.
The work will affect the M62 eastbound carriageway from the exit slip road at junction 32a to the entry slip road at junction 33.
The exit slip road from the southbound A1(M) to the eastbound M62 will be closed as well as the eastbound exit slip road from the junction 32a of the M62 to the northbound A1(M).
Clearly signed diversions will be in place during the closures. It is expected to take around 2 weeks to complete.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.
Published 9 November 2015