Contractors for Highways England will be undertaking essential resurfacing work between the A616 Flouch roundabout and the A57 Gun Inn junction from Monday 16 November.
The 14 mile stretch of the A628 will be closed between 8pm and 6am Monday to Thursday to allow the work to take place.
As part of the scheme reflective road studs will be replaced and road markings will be repainted.
Highways England project manager Tim Calvert said:
This is essential maintenance work and we need to close the A628 overnight when traffic levels are at their lowest.
We are aware that there are other roadworks taking place along the diversion route, including the smart motorway scheme between junctions 39 and 42 on the M1. However the additional delays resulting from this are expected to be minimal. It is important that the resurfacing work on the A628 takes place before the winter months so drivers can benefit from smoother journeys.
Clearly signed diversions will be in place while the work takes place. Eastbound traffic will be diverted off the A628 at the Gun Inn junction onto the A57 to Sheffield. Westbound traffic will be advised of the closure on the M1 and diverted north via the M1, M62 and M60. The work is expected to be completed over 4 nights between 16 and 19 November but may extend into the following week depending on weather conditions.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.