Closed consultation

Consultation on the International Council for Harmonisation Guideline E20 for adaptive clinical trial design

• From: Medicines and Healthcare products Regulatory Agency
• Published: 24 July 2025

We are analysing your feedback

Visit this page again soon to download the outcome to this public feedback.

Summary

The MHRA is consulting with UK stakeholders to gather feedback and comments on ICH E20, a new international guideline.

This consultation ran from
12:01am on 24 July 2025 to 11:59pm on 30 November 2025

Consultation description

The MHRA is consulting with UK stakeholders to gather feedback and comments on a new international guideline on the design, conduct, analysis, and interpretation of adaptive clinical trials that provides a transparent and harmonised set of principles for the regulatory review of these studies in a global drug development program.

Documents

ICH E20 Public Consultation

HTML

Published 24 July 2025