Decision

Orphan register

Updated 12 December 2025
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Orphan registered products are listed in alphabetical order by trade name on the downloadable or browser view CSV file below. The file may be searched by pressing “CTRL+F” and entering a key word or phrase. Where you are instructed to see a numbered section for more information, you can do so in the Summary of Product Characteristics (SmPC) for each product.
Product name
ABECMA
Adzynma
AGAMREE
Akantior
ALPROLIX
ALYFTREK
AMGLIDIA
ARIKAYCE liposomal
Artesunate Amivas
ASPAVELI
Aucatzyl
Avacopan Vifor
Avacopan Vifor
AYVAKYT
AYVAKYT
Besponsa
BLINCYTO
Brineura
Bylvay
Cablivi
Carvykti
Casgevy
Casgevy
Cerdelga
Chenodeoxycholic acid Leadiant
Coagadex
Cresemba
Cresemba
CRYSVITA
Cystadrops
Darzalex
Darzalex
Daurismo
Dovprela
Duvyzat
Ebvallo 2.8 x 10^7 - 7.3 x 10^7 cells/mL dispersion for injection
Ekterly
ELZONRIS
Enspryng
Epidyolex
Epidyolex
Epidyolex
Ezmekly
FABHALTA
FABHALTA????
Filspari
FILSUVEZ
FINLEE
Fintepla
Fintepla
Galafold
Gilteritinib Astellas 40mg film-coated tablets
Givlaari
Hemgenix 1 x 10^13 genome copies/mL concentrate for solution for infusion
Holoclar
Hyftor
Idefirix
IDELVION
Imcivree
Imcivree
IMDYLLTRA 1 milligram and 10mg powder for concentrate and solution for infusion
Inrebic
IQIRVO
Isturisa
Ixazomib
Joenja
Jorveza
Kaftrio
KIMMTRAK
Kinpeygo
Koselugo
Kymriah
Kymriah
Kymriah
Lamzede
Ledaga
Libmeldy
LIVMARLI
LIVTENCITY
LIVTENCITY
Loargys 5 mg/ml solution for injection/infusion
Lonapegsomatropin Ascendis Pharma
LUNSUMIO
Lutathera
Luxturna
Luxturna
Mepsevil
Minjuvi
Myalepta
Myalepta
Myalepta
Myalepta
Mylotarg
Namuscla
Natpar
Nexviadyme 100 mg powder for concentrate for solution for infusion
Ngenla
Ocaliva
Onivyde pegylated liposomal
Onpattro
Opfolda
OXBRYTA
Oxlumo
Pemazyre
Polivy
Pombiliti 105 mg powder for concentrate for solution for infusion
Poteligeo
PREVYMIS
PYRUKYND
Qalsody
Qarziba
QINLOCK
Ravicti
Ravicti
Ravicti
Ravicti
Ravicti
Ravicti
Reblozyl
REZUROCK
Rezzayo
Rydapt
Rydapt
Rystiggo 140 mg/ml solution for injection
Scemblix
Skyclarys 50 mg hard capsules
Sogroya
Soliris
Soliris
SomaKit TOC
Spexotras
Spinraza
Strimvelis
Symkevi
TAKHZYRO
Tecartus
Tecartus
Tegsedi
TIBSOVO
TIBSOVO
Trecondi
Trepulmix
UPSTAZA
Vanflyta
Verkazia
Voraxaze 1000 units powder for solution for injection
Vyloy
Vyndaqel
Vyvgart 20 mg/ml Concentrate for solution for infusion
Vyvgart 1000 mg solution for injection)
Vyvgart 1000 mg solution for injection in pre-filled syringe
Vyxeos liposomal
Wainzua
Waylivra
Winrevair
XENPOZYME
Xermelo
Yescarta
Yescarta
Yescarta
Yorvipath 168 micrograms/0.56 mL solution for injection in pre filled pen
Yorvipath 294 micrograms/0.98 mL solution for injection in pre filled pen
Yorvipath 420 micrograms/1.4 mL solution for injection in pre filled pen
Zejula
Zokinvy
Zolgensma
Ztalmy 50 mg/ml Oral suspension