Decision
Expired orphan registrations
Updated 12 December 2025
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| A list of orphan authorisations previously registered by the UK Licensing Authority where the orphan market exclusivity period has ended or the orphan designation has been removed. Products are listed in alphabetical order by trade name on the downloadable or browser view CSV file below. The file may be searched by pressing “CTRL+F” and entering a key word or phrase. |
|---|
| Product name |
| ADAKVEO |
| ADCETRIS |
| ADCETRIS |
| Adempas |
| AMVUTTRA |
| Bronchitol |
| Carbaglu |
| Carbaglu |
| Carbaglu |
| Cerdelga |
| Columvi 2.5 mg and 10mg concentrate for solution for infusion |
| Cometriq |
| Dacogen |
| Defitelio |
| Esbriet |
| Evrysdi |
| Farydak |
| Gazyvaro |
| Gazyvaro |
| Granupas |
| Hepcludex |
| Hetlioz |
| Iclusig |
| Iclusig |
| Imnovid |
| Kalydeco |
| Kalydeco |
| Kanuma |
| Ketoconazole HRA |
| Kyprolis |
| Mozobil |
| Nexavar |
| Nexavar |
| NexoBrid |
| Obiltoxaximab SFL |
| Opsumit |
| Plenadren |
| Raxone |
| Revestive |
| SCENESSE |
| Signifor |
| Signifor |
| Sirturo 20 mg Tablets |
| Soliris |
| Strensiq |
| Sylvant |
| TOBI Podhaler |
| Translarna |
| Vimizim |
| VPRIV |
| Vyndaqel |
| Welireg |
| Xaluprine |
| Zynteglo |