We use some essential cookies to make this website work.
We’d like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services.
We also use cookies set by other sites to help us deliver content from their services.
You have accepted additional cookies. You can change your cookie settings at any time.
You have rejected additional cookies. You can change your cookie settings at any time.
Departments, agencies and public bodies
News stories, speeches, letters and notices
Detailed guidance, regulations and rules
Reports, analysis and official statistics
Consultations and strategy
Data, Freedom of Information releases and corporate reports
How to apply for a clinical trial including eligibility, phases, model IMPDs, costs and how to make changes to your application.
How to show the MHRA you're meeting good clinical practice (GCP) standards and what to expect from an inspection.
Change your protocol, update your authorisation, report safety issues, submit safety updates and complete your end-of-trial study report.
Guidance on the process for ending a clinical trial.
Past and current clinical trials into therapeutic and antiviral treatments for COVID-19, how to take part, and which treatments have proven to be effective.
How to notify the MHRA of your intention to carry out a clinical investigation for medical devices.
Guidance on the collection, verification, and reporting of safety events in clinical trials of an investigational medicinal product.
How to apply for a clinical trial from 28 April 2026, including eligibility, documentation and registration in a public registry.
Guidance and reports on the Department for Transport's trial of longer semi-trailers for articulated goods vehicles.
How investigators and sponsors should manage clinical trials during COVID-19
Don’t include personal or financial information like your National Insurance number or credit card details.
To help us improve GOV.UK, we’d like to know more about your visit today. Please fill in this survey (opens in a new tab and requires JavaScript).