In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

Journal article in Reproductive Toxicology

From:
Department for International Development
Published
1 June 2014
Document Type:
Journal Article
Theme:
Health
Authors:
Longo, M, Zanoncelli, S, Messina, M, Scandale, I, Mackenzie, C, Geary, T, Marsh, K, Lindley, D, Mazue, G

Abstract

Flubendazole, in a new formulation with high systemic bioavailability, has been proposed as a macrofilaricide against filarial diseases. The embryotoxic activity of a new oral flubendazole formulation was investigated. It did not interfere with rat embryofetal development.

This research is part of the Drugs for Neglected Diseases initiative (DNDi)

Citation

Longo M, Zanoncelli S, Messina M, Scandale I, Mackenzie C, Geary T, Marsh K, Lindley D, Mazué G.(2014) In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses. Reproductive Toxicology Volume 49, November 2014, Pages 33-42 https://doi.org/10.1016/j.reprotox.2014.06.009

In vivo preliminary investigations of the effects of the benzimidazolen anthelmintic drug flubendazole on rat embryos and fetuses

Published 1 June 2014
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