Development of a scalable process for the synthesis of DNDI-VL-2098: A potential preclinical drug candidate for the treatment of VL

A study on the treatment of visceral leishmaniasis

From:
Department for International Development
Published
1 December 2016
Document Type:
Journal Article
Theme:
Health
Authors:
Satam, Vijay S

Abstract

This study describes the elaboration of a process suitable for the kilogram scale synthesis of DNDI-VL-2098, a preclinical candidate for the treatment of visceral leishmaniasis.

This research was funded by the Drugs for Neglected Diseases initiative (DNDi) programme

Citation

Vijay S. Satam, Rao Pedada S, Kamaraj P, Antao N, Singh A, Hindupur RM, Pati HN, Thompson AM, Launay D, Martin D.(2016) Development of a scalable process for the synthesis of DNDI-VL-2098: A potential preclinical drug candidate for the treatment of VL. Org. Process Res. Dev., 2017, 21 (1), pp 52–59 DOI: 10.1021/acs.oprd.6b00331

Development of a scalable process for the synthesis of DNDI-VL-2098: A potential preclinical drug candidate for the treatment of VL

Published 1 December 2016
Contents