Corporate report

Number of animals used: 2014 to 2016

Updated 12 July 2021

The following tables provide the numbers of animals used, per species, at our scientific campuses at Porton, Colindale and Chilton, from 2014 to 2016.

Read more about how and why we use animals in research.

PHE Porton (includes Porton Biopharma Limited)

Year Mice Hamsters Ferrets Guinea pigs Rabbits Non-human primates (NHP)
2016 2435 162 269 3132 92 63
2015 3896 136 400 2838 192 72
2014 4347 257 213 4064 51 133

The research includes studies that help us understand the body’s response to disease. For example, ferrets are used as models to study diseases caused by influenza viruses as their respiratory system has many similarities to that of humans.

Hamsters are the model of choice for Clostridium difficile (C.diff) infection and work has led to the clinical application of new treatments against this highly infectious disease that affects many hospital patients. Non-human primates are used only when other species are considered not to be suitable and are typically used where a therapy or vaccine is near to use in the clinic due to their close similarity to human immunology and physiology. In the majority of cases, the procedures conducted are of minimal impact on animal welfare and involve vaccination in the same way that humans are immunised.

PBL’s work is focussed on quality-assured development of biopharmaceuticals including Erwinase, a childhood leukaemia therapy, and the UK’s anthrax vaccine and their work mainly involves the use of guinea pigs and mice.

PHE Colindale

Year Mice Ferrets Turkeys Guinea pigs Rabbits
2016 32 4 16 53 3
2015 96 7 16 52 13
2014 36 9 16 53 18

The use of rabbits for enteric antisera work has been discontinued and replaced with whole genome sequencing technology.

PHE Chilton (Centre for Radiation, Chemical and Environmental Hazards)

Year Mice Rats
2016 2338 10
2015 2206 58
2014 1203 74

The research includes the study of radiation-induced acute myeloid leukaemia and intestinal cancer, and responses to toxic stress caused by chemicals or nanoparticles, and the neurobiological effects of electromagnetic fields.