Transparency data

Non-tech summaries 2016: projects on musculoskeletal disorders

Projects granted during 2016 that have a primary purpose of translational applied research - human musculoskeletal disorders.

Documents

Non-technical summaries: projects granted in 2016, volume 22

This file may not be suitable for users of assistive technology. Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email alternativeformats@homeoffice.gsi.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of translational applied research - human musculoskeletal disorders.

The following projects were granted:

  • enhancement of bone repair and bone ingrowth (bone, biocompatibility, repair, ingrowth)

  • mechanisms of skeletal repair and pain (fractures, bone, joint, pain)

  • joint tissue remodelling in health and arthritis (arthritis cartilage joint ageing)

  • cell-matrix interaction in health and disease (integrin, basement membrane, regeneration, stem cell)

  • new treatments for heterotopic ossification (heterotopic ossification, trauma, treatment, bone)

  • therapy of rheumatoid arthritis (rheumatoid arthritis, treatment, animal models)

  • models and therapy for congenital myasthenia (myasthenia, NMJ, AChR, DOK7, beta2-agonists)

  • cartilage repair using circulating stem cells (cartilage progenitor)

  • mechanisms and treatments of craniofacial birth defects (craniosynostosis, cleft palate, FGF, crouzon, craniofacial)

  • cell-extracellular matrix interactions and diseases (liver, tendon, extracellular matrix, fibrosis)

  • chorioallantoic membrane model for tissue engineering (chorioallantoic, skeletal, angiogenesis, tissue, engineering)

  • non-coding genes in osteoarthritis and musculoskeletal ageing (snoRNAs, osteoarthritis, ageing, murine, cartilage)

  • controlling osteoarthritis progression (osteoarthritis, ageing, trauma, mouse)

  • assessing biomaterial and cell transplant strategies for bone formation (biomaterials, scaffold degradation, bone formation, stem cells)

  • developing drugs to treat myotonic dystrophy (myotonic dystrophy, drugs screen, animal model)

Published 21 December 2017