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Non-tech summaries 2016: projects on musculoskeletal disorders

Projects granted during 2016 that have a primary purpose of translational applied research - human musculoskeletal disorders.

• From: Home Office
• Published: 21 December 2017

Documents

Non-technical summaries: projects granted in 2016, volume 22

PDF, 351 KB, 51 pages

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Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of translational applied research - human musculoskeletal disorders.

The following projects were granted:

• enhancement of bone repair and bone ingrowth (bone, biocompatibility, repair, ingrowth)

• mechanisms of skeletal repair and pain (fractures, bone, joint, pain)

• joint tissue remodelling in health and arthritis (arthritis cartilage joint ageing)

• cell-matrix interaction in health and disease (integrin, basement membrane, regeneration, stem cell)

• new treatments for heterotopic ossification (heterotopic ossification, trauma, treatment, bone)

• therapy of rheumatoid arthritis (rheumatoid arthritis, treatment, animal models)

• models and therapy for congenital myasthenia (myasthenia, NMJ, AChR, DOK7, beta2-agonists)

• cartilage repair using circulating stem cells (cartilage progenitor)

• mechanisms and treatments of craniofacial birth defects (craniosynostosis, cleft palate, FGF, crouzon, craniofacial)

• cell-extracellular matrix interactions and diseases (liver, tendon, extracellular matrix, fibrosis)

• chorioallantoic membrane model for tissue engineering (chorioallantoic, skeletal, angiogenesis, tissue, engineering)

• non-coding genes in osteoarthritis and musculoskeletal ageing (snoRNAs, osteoarthritis, ageing, murine, cartilage)

• controlling osteoarthritis progression (osteoarthritis, ageing, trauma, mouse)

• assessing biomaterial and cell transplant strategies for bone formation (biomaterials, scaffold degradation, bone formation, stem cells)

• developing drugs to treat myotonic dystrophy (myotonic dystrophy, drugs screen, animal model)

Published 21 December 2017