Transparency data

Non-tech. summaries 2015: projects on the gastrointestinal system

Projects granted during 2015 that have a primary purpose of basic research: gastrointestinal system including liver.

Document

Non-technical summaries: projects granted in 2015, volume 21

This file may not be suitable for users of assistive technology. Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email alternativeformats@homeoffice.gsi.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of basic research: gastrointestinal system including liver.

The following projects were granted:

  • intestinal carcinogenesis studies (cancer, intestine, radiation, x-rays)

  • troy+ stem cells in homeostasis, repair and cancer (stem cells, dynamics, hierarchy, tissue regeneration)

  • understanding liver fibrosis using rat models (liver disease, scar, rat, therapy)

  • molecular basis of enteric bacterial infections (bacteria, infection, diarrhoea, e.coli)

  • cell death, inflammation and cancer in the GI tract (intestine, stomach, apoptosis, inflammation, cancer)

  • intestinal barrier function: the role of epithelial and immune cells (intestine, immune cell, epithelium, microflora, SOCS3)

  • dietary manipulation or supplementation on rumen function (rumen, diet, bolus, acidosis, fistula)

  • understanding inflammation, fibrosis and cancer (scarring, liver cancer, drugs)

  • periostin in nerve regeneration and IBD (inflammation, inflammatory bowel disease, regeneration, nerves)

  • adaptations of the host and pathogen during infection (clostridium difficile, escherichia coli, inflammation, diet, gut)

  • gut tumorigenesis (intestine cancer, polyp, crypt)

Published 24 June 2016