Transparency data

Non-tech. summaries 2015: projects on the endocrine system

Projects granted during 2015 that have a primary purpose of basic research: the endocrine system.

Documents

Non-technical summaries: projects granted in 2015, volume 26

This file may not be suitable for users of assistive technology. Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email alternativeformats@homeoffice.gsi.gov.uk. Please tell us what format you need. It will help us if you say what assistive technology you use.

Details

This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of basic research: the endocrine system/metabolism.

The following projects were granted:

  • mouse models of calcium and bone disorders (calcium homeostasis, bone dysplasias, parathyroid, kidney)

  • breeding and maintenance of genetically modified and mutant mice (mice, genetically modified, breeding, mutant)

  • discovery of healthy lean gene mechanisms (genes, healthy leanness, obesity, diabetes)

  • genetic control of endocrine development and tumorigenesis (pituitary, hormones, birth defects, tumours, genetics)

  • metabolism, pharmacokinetics and biomarkers (metabolism, pharmacokinetics, biomarkers, DMPK)

  • the origin of new β-cells in pregnancy (β-cells, pregnancy, transdifferentiation, 4OHT, transgenic)

  • cancer Pathways in Metabolic Disease (Metabolism, cancer, signalling pathways, therapy)

  • the physiological role of B3 vitamins in energy metabolism (energy, vitamin B31 nicotinamide adenine dinucleotide, mitochondria)

  • circadian control of behaviour and metabolism (obesity, diabetes, clock, biological rhythms, physiology)

  • embryogenesis, stem cells and cell fate decisions (stem cells, cell fate, embryogenesis)

  • extracellular regulation of insulin resistance (iInsulin, obesity, type 2 diabetes)

  • the mechanisms of ageing and age-related disease (ageing, age-related disease, healthspan)

  • endocrine action and endocrine cancer therapy (androgens, prostate, cancer, endocrine)

Published 28 June 2016