Transparency data

Non-tech. summaries 2015: projects on human cancer

Projects granted during 2015 that have a primary purpose of translational and applied research: projects on human cancer.


Non-technical summaries: projects granted in 2015, volume 15

This file may not be suitable for users of assistive technology. Request an accessible format.

If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email Please tell us what format you need. It will help us if you say what assistive technology you use.


This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2015 with a primary purpose of translational and applied research: projects on human cancer.

It contains a full list of the 22 projects that were granted.

The projects covered are:

  • imaging and image-guided therapy (in-vivo, imaging, cancer, mouse)

  • functions of dna repair genes in genome stability and cancer (DNA repair, cancer, genome stability)

  • mechanisms of brain cancer progression (brain, CNS, cancer, mouse)

  • novel immuno-oncology therapies (cancer, tumour, immunotherapies)

  • focus on the BRCA1 n-terminus in development and cancer (breast cancer, genetics)

  • imaging in drug discovery (non-invasive, medical imaging, drug discovery)

  • immunotherapy of cancer (immunology, cancer, vaccine, therapy, cure)

  • novel therapies for human cancer (cancer, tumour, drug)

  • RAC and RAC regulators in development and cancer (RAC, cancer initiation, metastasis)

  • evaluation of novel treatments for prostate cancer (prostate, androgen receptor, n-terminal domain, rotenoid)

  • using patient derived xenografts to study cancer (cancer, patient derived xenograft (PDX))

  • function of tetraspan complexes in carcinogenesis (tetraspan, integrin, kinase, tumourigenesis, metastasis)

  • translational chrono-oncology (biological clocks, cancer, pharmacology)

  • identifying and characterising the cellular drivers of adult acute lymphoblastic leukaemia (leukaemia mouse models)

  • investigation of normal and aberrant haemopoiesis (haemopoiesis, cancer, bone marrow failure, graft-versus-host disease)

  • biology of normal and malignant blood cells (leukaemia, cord blood, fusion gene, cytokine)

  • therapeutic antibodies for cancer (monoclonal antibody, immune therapy, cancer)

  • in vivo assessment of biomaterials (cancer therapies)

  • advanced nucleic acid and small molecule therapies for cancers (nucleic, acid, molecule therapies cancers)

  • radiation combinations for cancer treatments (radiation, rodent, cancer)

  • evaluation of therapeutics for the treatment of head and neck cancer (head and neck, thyroid, cancer, drug discovery)

  • therapeutic strategies to improve organ quality and function in a pig model (transplantation, retrieval, improve organ quality)

Published 21 June 2016