The package will see three sections of the road resurfaced, with work starting between Catchfrench and Lean Quarry overnight on Friday, 30 October.
Two other schemes will see resurfacing work carried out between Cartuther and South Trevido (eastbound) and Trerulefoot and Catchfrench (eastbound and westbound).
Highways England project sponsor Helen Phillips said,
We fully appreciate the A38 is a busy road and that is why we have planned these works to take place at a quieter time of the year and overnight to ensure disruption to road-users is kept to an absolute minimum.
When complete, the schemes will prolong the overall life of the carriageway and maintain safety.
All works have been programmed to take place between 7pm-6am and will require some overnight closures and some daytime lane restrictions.
The first section of resurfacing between Catchfrench and Lean Quarry will start on the night of Friday, 30 October and is expected to be completed on the morning of Thursday, 26 November. This work will start with five weekday nights of closures.
A further 14 weekday nights of work will be conducted under a convoy arrangement, which will allow traffic to remain on the A38, although held by traffic lights and taken in convoy past the roadworks at 10 mph to ensure the safety of our road workers and drivers.
The second section of work between Cartuther and South Trevido will start when the first phase has been completed, on the night of Thursday, 26 November and is expected to be completed on Tuesday, 8 December. This will require seven weekday nights of closures and daytime single lane closures.
The third section between Trerulefoot and Catchfrench will start on Monday, 7 December. It is expected to be completed on the morning of Thursday, 17 December and will require eight weekday nights of westbound carriageway closures. At the same time and for the same duration, works on the eastbound carriageway will be conducted under a convoy arrangement with only one lane being closed at a time and traffic being managed with temporary traffic lights.
Fully signed diversions routes will be in place during all road closures.
The works are part of a substantial £6 million programme of overnight resurfacing covering six sections of the A38 between Dartbridge and Trerulefoot .
Further details will be published as the programme progresses and we hope that works will be completed by December 18, subject to weather conditions.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.