The work between the junctions of Barton Road and Edgar Street includes resurfacing both carriageways, upgrading the signalled crossing at Barton Road, replacing road markings, studs and traffic detection loops, relocating and replacing lit bollards and installing tactile paving on the footpath.
The work will be carried out overnight, from 10.15pm to 6.30am in three phases.
The first which starts on Monday will require an overnight closure of the northbound carriageway, the second an overnight closure of the southbound and the third will require temporary access restrictions to Barton Road and St Nicholas Street.
The start dates for the second and third phases will be advertised in advance.
The work will be co-ordinated with Herefordshire Council’s work in Barton Road and St Nicholas Street to reduce disruption.
During the closures of the A49 Victoria Street traffic will be diverted along Barton road, Westfaling Street, the A4110 and A4103 Roman Road, or vice versa.
Members of the public should contact the Highways Agency Information Line on 0300 123 5000
Journalists should contact the Highways Agency press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer