The Highways Agency will be resurfacing a 200-metre section of the carriageway as well as replacing road markings, high friction surfacing and traffic detection loops.
The work takes place from 8pm to 6am each night with traffic diverted via the A4117 and A456 to rejoin the A49 at Woofferton.
Highways Agency Project Manager Richard Gulliver said:
The work will lead to an improved road surface. We will minimise disruption by carrying out the work at night and advise road users to allow extra time for their journeys.
Members of the public should contact the Highways Agency Information Line on 0300 123 5000
Journalists should contact the Highways Agency press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer