The three week scheme will be carried out overnight on the eastbound carriageway between the Wolfshead Roundabout and Felton Butler Roundabout between 8pm and 6am.
Traffic will be diverted through Nesscliffe.
Highways Agency Project Manager Purnima Kaul said:
Parts of the carriageway have suffered a number of defects over the winter. Carrying out this work will ensure the continued provision of a safe, smooth surface for road users.
Members of the public should contact the Highways Agency Information Line on 0300 123 5000
Journalists should contact the Highways Agency press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer