The joints allow structures to expand and contract with seasonal changes in temperature.
The work involves a full overnight closure of the A38 northbound carriageway between the Clay Mills junction and Toyota junction from 9pm to 5am.
Traffic will be diverted off the A38 at Burton and along the A5121, A511 and the A50.
Highways Agency project manager Colin Jackson said:
To carry out the work safely and efficiently we need to close the carriageway. We advise road users affected by the diversions to allow extra time for their journeys.
Members of the public should contact the Highways Agency Information Line on 0300 123 5000
Journalists should contact the Highways Agency press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.