The £1.7m project, which will take place at various locations between junctions 1A for the M25 and 10 at Ardley, will involve removing the old overhead message signs and replacing them with new models.
Highways England project manager Neil Doherty said:
This work will ensure better journeys for drivers as they will benefit from the latest technology to get up-to-date information about hazards or delays ahead.
We have timed the work to be minimise disruption but we are advising people to allow extra time for their journeys when closures are in place.
The first phase of work, to prepare the sites for the new signs, will be carried out in the roadside verges using hard shoulder closures only and should be completed by the end of January. Road users will not be affected during this phase.
The second phase to install and switch on the new signs, which will start in parallel on 25 January, will require overnight lane and slip roads closures, which will be clearly signposted in advance. During the slip road closures, there will be a clearly signed diversion diverting traffic via the next M40 junction.
The work is planned for completion in spring 2016, weather permitting.
For the up to date traffic information, visit the Highways England webpage or follow @HighwaysEAST in the East of England.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.