Contractors for Highways England will be resurfacing the southbound carriageway of the A1 between Alnwick and Newton on the Moor.
A contraflow system will be in place, with the southbound carriageway closed to traffic. Vehicles will run in both directions on the northbound carriageway.
Highways England project manager Steve Bishop said:
When complete, this project will provide drivers with safer and smoother journeys along this stretch of the A1 in Northumberland.
Every effort is being made to ensure disruption to traffic and residents is kept to a minimum, and we’ll be using a contraflow system on the northbound carriageway to keep vehicles running in both directions.
Traffic travelling north will be able to turn left off the carriageway but not right and traffic travelling south will not be able to turn left or right off the carriageway.
Clearly signed diversion routes will be in place for residents living off the A1 and these routes will be treated with salt if temperatures drop below freezing until the project is due to be completed at the end of next month.
The X15 Arriva bus service will be affected by the work but a shuttle bus has been arranged with Arriva to serve the villages of Hampeth and Shilbottle.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.