Contractors for Highways England will be carrying out patching work between Fenwick crossroads and West Mains crossroads, a distance of nearly 2 miles, will be closed overnight between 8pm and 6am.
Highways England project manager Steve Bishop said:
This is essential maintenance work that needs to be completed along the A1 and we will be carrying out this work overnight when traffic levels are at their lowest.
Once complete, drivers will benefit from an improved road surface. Each junction off the A1 between Fenwick and Oxford junctions will be closed during the work and manned by our traffic management team, so that drivers can either be escorted through the site to access properties or redirected to join the diversion route.
Clearly signed diversions will be in place via the B6353 and the B6525.
Members of the public should contact the Highways England customer contact centre on 0300 123 5000.
Journalists should contact the Highways England press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer.