The £50,000 project, which includes ditch cleaning, will start on Monday (17 March) with round the clock working around the slip road until Saturday March 22.
Road users normally leaving the eastbound A64 at the junction will need to leave a junction earlier at the Pickering Interchange and use the southbound B1257 to get to Brambling Fields via Malton.
Highways Agency project sponsor John Howard said:
This is routine maintenance to ensure road users can continue to use this slip road safely.
Members of the public should contact the Highways Agency Information Line on 0300 123 5000
Journalists should contact the Highways Agency press office on 0844 693 1448 and use the menu to speak to the most appropriate press officer