When prescribing or dispensing the Xalatan brand of latanoprost:
- advise patients to tell their health professional if they experience severe eye irritation
- review treatment if patients mention severe eye irritation
- please continue to report suspected side effects to latanoprost or any other medicines on a Yellow Card
Xalatan is an eye-drop formulation of latanoprost. It is licensed for the reduction of intraocular pressure in adults and children with ocular hypertension and open angle glaucoma.
In 2013, the Xalatan pH was reduced from 6.7 to 6.0 to allow for long-term storage at room temperature. Following this reformulation there has been an increase in the number of reports of eye irritation from across the EU. We received no Yellow Card reports of eye irritation in people using Xalatan in the year before the reformulation, compared with 22 reports in the year after reformulation.
It is important that patients continue their treatment. Therefore advise patients to tell their health professional promptly (within a week) if they have eye irritation (eg excessive watering) severe enough to make them consider stopping treatment. Review treatment and prescribe a different formulation if necessary.
Xalatan summary of product characteristics
Article citation: Drug Safety Update Volume 8 issue 12 July 2015: 2.