This was a laboratory-based method comparison study conducted at a rural district hospital in Beitbridge, Zimbabwe. It collected blood in conventional EDTA tubes requires laboratory analysis within 48 hours to provide valid CD4 cell count results. This restricts access to HIV care for patients from rural areas in resource-constraint settings due to sample transportation problems. Stabilization Tubes with extended storage duration have been developed but not yet evaluated comprehensively.
This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)
Vogt F, Van den Bergh R, Bernasconi A, Moyo B, Havazvidi L, Bastard M, et al. (2015) Using BD Vacutainer CD4 Stabilization Tubes for Absolute Cluster of Differentiation Type 4 Cell Count Measurement on BD FacsCount and Partec Cyflow Cytometers: A Method Comparison Study from Zimbabwe. PLoS ONE 10(8): e0136537. doi:10.1371/journal.pone.0136537
Using BD Vacutainer CD4 stabilization tubes for absolute cluster of differentiation type 4 cell count measurement on BD FacsCount and Partec Cyflow cytometers: a method comparison study from Zimbabwe