Women and girls are especially vulnerable to HIV infection in sub-Saharan Africa, and in some of those countries, prevalence among young women can be up to 3 times higher than among men of the same age. Effective HIV prevention options for women are clearly needed in this setting. Several ARV-based vaginal microbicides are currently in development for prevention of HIV transmission to women and are discussed here. The concept of pre-exposure prophylaxis for the prevention of HIV transmission to women is introduced.
Mertenskoetter, T.; Kaptur, P.E. Update on microbicide research and development - seeking new HIV prevention tools for women. European Journal of Medical Research (2011) 16 (1) 1-6.