Unfavourable outcomes among patients with MDR-TB on the standard 24-month regimen in Maharashtra, India
Assesses the timing and risks for unfavourable treatment outcomes, focus on death and loss to follow-up
Abstract
Setting
Patients with multidrug-resistant tuberculosis (MDR-TB) registered for treatment (2011–2012 cohort) using the standard 24-month regimen, under the Revised National TB Control Programme’s programmatic management of drug-resistant TB (PMDT), Maharashtra, India
Objectives
To assess the treatment outcomes and the timing and risk factors for unfavourable treatment outcomes, with a focus on death and loss to follow-up (LTFU).
Method
This was a retrospective cohort study involving a review of PMDT records. Treatment outcomes were reported on 31 December 2014.
Conclusion
The study found poor treatment outcomes in patients with MDR-TB registered for treatment in Maharashtra, India. Interventions are required to address the high rates of LTFU and death.
This research was supported by the UK Department for International Development’s Operational Research Capacity Building Programme led by the International Union Against TB and Lung Disease (The Union)
Citation
Suryawanshi SL, Shewade HD, Nagaraja SB, Nair SA, Parmar M. Unfavourable outcomes among patients with MDR-TB on the standard 24-month regimen in Maharashtra, India. Public Health Action. 2017;7(2):116–22.