Understanding clinical research studies - March 2005. What information can clinical research studies provide?


Before Phase III trials begin, researchers use clinical research studies to determine the practicality of conducting research in a given community and ready a trial site and community for future vaccine (and other HIV) research trials. Such studies provide critical information about how to design efficacy trials and in which populations it is most appropriate to test vaccine candidates. Prevalence and incidence studies, studies of early infection and baseline referencing studies are described.


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